Evidence map›Paper›PMID 41357228›Full record

ReviewFrontiers in immunology2025

Immune functions of avian erythrocytes: a comprehensive review from basic biology to pathogen-induced responses.

Fujuan Cai, Yuzhen Wang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fujuan CaiSchool of Life Sciences, Inner Mongolia Key Laboratory of Biomanufacturing Technology, Inner Mongolia Agricultural University, Hohhot, China.
Yuzhen WangSchool of Life Sciences, Inner Mongolia Key Laboratory of Biomanufacturing Technology, Inner Mongolia Agricultural University, Hohhot, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Avian erythrocytes, traditionally perceived as mere oxygen transporters, are increasingly acknowledged as integral components of the immune system. Unlike enucleated erythrocytes of mammals, avian erythrocytes retain functional nuclei and organelles, allowing them to produce immune molecules like cytokines and antimicrobial peptides essential for pathogen recognition and clearance. This review provides a comprehensive elucidation of the molecular mechanisms underpinning the immune functions of avian erythrocytes and their responses to infections induced by viruses, bacteria, fungi,

Indexed as

Bird DiseasesBirdsErythrocytesAnimalsApoptosisHost-Pathogen InteractionsOxidative StressPhagocytosisSignal TransductionToll-Like ReceptorsToll-Like Receptorsavian erythrocytescytokinesimmune responsesoxidative stressphagocytosistoll-like receptors (TLRs)

Identifiers

PMID41357228
PMCPMC12675249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.