Evidence map›Paper›PMID 41357204›Full record

ArticleFrontiers in immunology2025

Immunization with the M12-N, M12-C, and M12-N+C fusion peptides derived from the M12 protein elicited varying levels of protective immune responses against multiple serotypes of group A

Xiaolan Zhang, Yue Ma, Rige Na, Wenli Hou, Emanuel Hanski, Qin Zhou

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaolan ZhangSchool of Basic Medical Sciences, Harbin Medical University, Harbin, China.
Yue MaSchool of Basic Medical Sciences, Harbin Medical University, Harbin, China.
Rige NaSchool of Basic Medical Sciences, Harbin Medical University, Harbin, China.
Wenli HouChengdu Ruiyi Biotechnology Co., Ltd., Chengdu, China.
Emanuel HanskiDepartment of Microbiology and Molecular Genetics, The Institute for Medical Research, Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Qin ZhouSchool of Basic Medical Sciences, Harbin Medical University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The M protein located on the surface of group A

Indexed as

Antigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsStreptococcal InfectionsStreptococcal VaccinesStreptococcus pyogenesAnimalsAntibodies, BacterialFemaleImmunizationMiceMice, Inbred BALB CRecombinant Fusion ProteinsSerogroupTh1 CellsAntibodies, BacterialAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsRecombinant Fusion Proteinsstreptococcal M proteinStreptococcal Vaccinesgroup A streptococcusinfectionketosteroid isomeraseM peptideprotective efficacyvaccine

Identifiers

PMID41357204
PMCPMC12678301

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.