Evidence map›Paper›PMID 41357154›Full record

ArticleJournal of the American Statistical Association2025

Checking the Cox Proportional Hazards Model with Interval-Censored Data.

Yangjianchen Xu, Donglin Zeng, D Y Lin

Abstract read
In one paragraph

Article in Journal of the American Statistical Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yangjianchen XuDepartment of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada.ORCID 0000-0002-1229-0477
Donglin ZengDepartment of Biostatistics, University of Michigan, Ann Arbor, MI.
D Y LinDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Funding

Statistical and Machine Learning Methods to Improve Dynamic Treatment Regimens Estimation Using Real World Data.R01GM124104 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Yuanjia Wang, Donglin Zeng · 2018 to 2026
$3.1M
Semiparametric Regression Analysis of Interval-Censored Data in Current Cohort StudiesR01HL173128 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Donglin Zeng · 2024 to 2026
$1.2M
NHLBI NIH HHS R01 HL173128NIGMS NIH HHS R01 GM124104
6 · The paper itself

Abstract

This article presents a general framework for checking the adequacy of the Cox proportional hazards model with interval-censored data, which arise when the event of interest is known only to occur over a random time interval. Specifically, we construct certain stochastic processes that are informative about various aspects of the model, that is, the functional forms of covariates, the exponential link function and the proportional hazards assumption. We establish their weak convergence to zero-mean Gaussian processes under the assumed model through empirical process theory. We then approximate the limiting distributions by Monte Carlo simulation and develop graphical and numerical procedures to check model assumptions and improve goodness of fit. We evaluate the performance of the proposed methods through extensive simulation studies and provide an application to the Atherosclerosis Risk in Communities Study. Supplementary materials for this article are available online, including a standardized description of the materials available for reproducing the work.

Indexed as

Goodness of fitInterval censoringModel misspecificationProfile likelihoodTransformation

Identifiers

PMID41357154
PMCPMC12680065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.