Evidence map›Paper›PMID 41357149›Full record

ArticleEvolution letters2025

Gene expression evolution is predicted by stronger indirect selection at more pleiotropic genes.

Eva L Koch, Charles Rocabert, Champak Beeravolu Reddy, Frédéric Guillaume

Abstract read
In one paragraph

Article in Evolution letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eva L KochDepartment of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0001-8366-4897
Charles RocabertOrganismal and Evolutionary Biology Research Programme, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-9224-5819
Champak Beeravolu ReddyDepartment of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-0800-1994
Frédéric GuillaumeDepartment of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-0874-0081

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in gene expression levels are central to adaptation, yet predicting and understanding their evolution remains challenging. Here, we used transcriptome-wide variation in the red flour beetle

Indexed as

evolvabilityexperimental evolutionG-matrixparallel evolutionRNA-seqRobertson–Price equation

Identifiers

PMID41357149
PMCPMC12676468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.