SynthesisFrontiers in cardiovascular medicine2025
Dietary inflammatory index and cardiovascular risk and mortality: an updated systematic review and meta-analysis.
Synthesis in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Food inflammation index and risks of all-cause and cardiovascular mortality among individuals with cardiovascular-kidney-metabolic syndrome: a nationally representative cohort study from NHANES 1999-2018.Scientific reports · 2026Article
- Association between hypertension and dietary inflammatory index among adults: a cross-sectional study in Hainan, China.Frontiers in nutrition · 2026Article
- Dietary index for gut microbiota score is inversely associated with carotid calcified plaque score in ischemic stroke patients.Frontiers in nutrition · 2026Article
- Inflammatory dietary scores and their association with clinical outcomes in coronary heart disease.Frontiers in nutrition · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Background: Cardiovascular diseases (CVDs) are the leading cause of death globally, and chronic inflammation is pivotal in CVDs development. Pro-inflammatory diets may exacerbate inflammation and thus increase CVDs risk. The Dietary Inflammatory Index (DII) is a validated measure of the inflammatory potential of diet. This updated systematic review and meta-analysis was conducted to clarify the association between DII and CVDs incidence and mortality. Methods: A comprehensive search was conducted in Pub Med, Web of Science, Embase, Cochrane Library, and China National Knowledge Infrastructure (CNKI) until February 2025. Study quality was assessed using the Newcastle-Ottawa Scale ( Results: Thirty cohort studies (NOS ≥7) from nine countries, involving 669,205 participants, were included. Compared with the lowest DII category, the highest category was associated with increased risks of CVD incidence [HR = 1.23, 95% CI (1.14-1.33); Conclusion: Higher DII scores, reflecting pro-inflammatory dietary patterns, are significantly associated with increased risks of CVD incidence and mortality. These findings underscore the clinical and public health importance of promoting anti-inflammatory dietary strategies to mitigate the global CVD burden. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420250654615, PROSPERO, CRD420250654615.
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