Evidence map›Paper›PMID 41357030›Full record

ArticleCureus2025

Recurrent Pericarditis in a Patient With Ankylosing Spondylitis: A Report of a Rare Case.

Constantin Sitari, Nicolae Sitari, Isabel Rodrigues, Rosario Blanco Sáez, Alexandra Martins

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Constantin SitariDepartment of Internal Medicine, Unidade Local de Saúde do Algarve - Hospital de Faro, Faro, PRT.
Nicolae SitariDepartment of Cardiology, Institutul de Boli Cardiovasculare "Prof. Dr. George I. M. Georgescu", Iași, ROU.
Isabel RodriguesDepartment of Internal Medicine, Unidade Local de Saúde do Algarve - Hospital de Faro, Faro, PRT.
Rosario Blanco SáezDepartment of Internal Medicine, Unidade Local de Saúde do Algarve - Hospital de Faro, Faro, PRT.
Alexandra MartinsDepartment of Internal Medicine, Unidade Local de Saúde do Algarve - Hospital de Faro, Faro, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Only a small subset of patients with ankylosing spondylitis (AS) develop cardiac complications, and pericardial inflammation is particularly uncommon. We report a 31-year-old human leukocyte antigen B27 (HLA-B27)-positive man with AS diagnosed in 2018 who, after discontinuing golimumab in 2021, experienced two episodes of acute pericarditis in 2025. In March, he presented with fever and chest pain. The electrocardiogram (ECG) showed diffuse, mild concave ST-segment elevation; chest computed tomography (CT) demonstrated a circumferential pericardial effusion measuring 24 mm with bilateral pleural effusions, consistent with polyserositis, and transthoracic echocardiography (TTE) confirmed a 15-17 mm fibrinous effusion without tamponade. He improved with colchicine and a corticosteroid taper. In August, he returned with pleuritic chest pain; the ECG revealed sinus tachycardia with diffuse ST elevation and PR-segment depression, and echocardiography showed a thin residual effusion. Bacterial and viral infections (including multiplex testing for respiratory and enteroviral pathogens and serology for cytomegalovirus, Epstein-Barr virus, and parvovirus B19), HIV, hepatitis B and C, and autoimmune causes were systematically excluded, and there were no clinical or imaging features to suggest malignancy. Taken together, the relapse and overall context favored attribution to AS-related inflammation. This case underscores the need to keep pericarditis in mind when patients with AS present with chest pain and to align pericarditis therapy with control of the underlying disease.

Indexed as

ankylosing spondylitisanti-tnfechocardiographyelectrocardiographypericardial effusionpericarditisrecurrent pericarditis

Identifiers

PMID41357030
PMCPMC12680922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.