Evidence map›Paper›PMID 41357016›Full record

ArticleCureus2025

Headache and Neurological Symptoms Following Lumbar Puncture in a Patient With a Ventriculoperitoneal Shunt.

Nicholas Koenig, Stephen Howell, Arpan Kohli, Jason Shepherd

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicholas KoenigAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.
Stephen HowellAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.
Arpan KohliAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.
Jason ShepherdAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-dural puncture headache (PDPH) is a common complication of lumbar puncture and neuraxial anesthesia, typically resulting from cerebrospinal fluid (CSF) leakage and intracranial hypotension. Although the pathophysiology and management of PDPH are well established in the general population, its diagnosis and treatment in patients with ventriculoperitoneal shunts pose unique challenges due to altered CSF dynamics and intracranial compliance. In these individuals, even minor CSF volume changes can produce unpredictable pressure gradients and paradoxical phenomena such as low-pressure hydrocephalus. The use of an epidural blood patch, a mainstay of PDPH management, carries additional risks in this population and must be approached with multidisciplinary collaboration and careful hemodynamic consideration.

Indexed as

epidural blood patchfocal seizuresinjection drug usepost-dural puncture headacheventriculo-peritoneal shunt surgery

Identifiers

PMID41357016
PMCPMC12680287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.