Evidence map›Paper›PMID 41356966›Full record

ArticleCureus2025

Clinically Silent Gangrenous Cholecystitis: A Case Report of Two-Week Survival Following Spontaneous Gallbladder Perforation Without Intervention.

Sarah Al-Zaher, German A Almonte Hidalgo

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarah Al-ZaherSurgical Gastroenterology, William Carey University College of Osteopathic Medicine, Hattiesburg, USA.
German A Almonte HidalgoGeneral Surgery, William Carey University College of Osteopathic Medicine, Hattiesburg, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous gallbladder perforation is an infrequent but life-threatening complication of acute cholecystitis, often associated with rapid clinical deterioration and high mortality. Prompt diagnosis and surgical intervention are critical. Atypical presentations in gallbladder perforation, especially if silent, often delay recognition and treatment, increasing the risk of adverse outcomes. We present the case of a 68-year-old male who presented to the emergency department with generalized weakness. Notably, he reported an episode of severe abdominal pain two weeks prior, which had since resolved. Vital signs and physical exam were normal. Imaging demonstrated pneumobilia and a pericholecystic fluid collection consistent with a contained gallbladder perforation. The patient underwent urgent laparoscopic cholecystectomy, which revealed a mid-body gallbladder perforation with extensive gallstone spillage and purulent drainage. Pathology confirmed gangrenous cholecystitis. He recovered uneventfully following surgery and was discharged on postoperative day seven, with no complications noted at his two-week follow-up. This case illustrates a rare presentation of a type II gallbladder perforation that remained clinically silent for two weeks, without signs of peritonitis or systemic compromise. Clinicians must maintain a high index of suspicion for serious intra-abdominal pathology in elderly patients presenting with vague or atypical symptoms, to ensure timely diagnosis and intervention in cases of gallbladder perforation.

Indexed as

acute cholecystitisbiliary pathologycase reportcontained perforationgallbladder perforationgangrenous cholecystitislaparoscopic cholecystectomytype ii gallbladder perforation

Identifiers

PMID41356966
PMCPMC12678009

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.