ArticleCureus2025
Eosinophilic Fasciitis in a Young Adult: A Rare Presentation Potentially Triggered by the Epstein-Barr Virus.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Eosinophilic fasciitis (EF) is a rare fibroinflammatory disorder that may mimic systemic autoimmune disease or hematologic malignancy. We report the case of a 19-year-old male patient who presented with progressive swelling, stiffness, and burning pain of the extremities. Laboratory studies were significant for inflammatory marker elevation and polyclonal hypergammaglobulinemia. Epstein-Barr virus (EBV) testing demonstrated a positive polymerase chain reaction (PCR) test and IgG with negative IgM, suggesting prior infection with possible viral reactivation. Imaging showed splenomegaly and diffuse fascial edema, and a deep fascial biopsy confirmed EF. The patient was treated with high-dose corticosteroids with rapid clinical improvement. This case highlights the diagnostic complexity of EF and raises the possibility of EBV as an immunologic trigger.
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