Evidence map›Paper›PMID 41356906›Full record

ArticleCureus2025

Lumbar Arachnoid Cyst Presenting as Arachnoiditis on MRI: A Case Report and Diagnostic Approach.

Alex A Dos Santos, Anuksha Varghese, Ammar Al-Amour, Mansour Afshani, Nora Nikprelevic, Parker Mckethan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alex A Dos SantosRadiology, American University of the Caribbean, Miami, USA.
Anuksha VargheseMedicine, Ross University School of Medicine, Miami, USA.
Ammar Al-AmourMedicine, Jordan University of Science and Technology, Irbid, USA.
Mansour AfshaniNeurology, Cleveland Clinic Florida, Weston, USA.
Nora NikprelevicNeurology, Cleveland Clinic Florida, Weston, USA.
Parker MckethanNeurology, Cleveland Clinic Florida, Weston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lumbar arachnoid cysts (ACs) and arachnoiditis may appear similar on magnetic resonance imaging (MRI) and may appear difficult to diagnose accurately. Considering that lumbar arachnoid cysts have a benign source, in contrast to arachnoiditis, surgical intervention poses a challenge. We present a case initially assumed to be arachnoiditis but later confirmed as an arachnoid cyst by MRI and computed tomography (CT) myelogram. The goal of this report was to provide a clearer understanding of the pathophysiological differences and key diagnostic features, including imaging techniques and clinical presentations that distinguish these two conditions. A 46-year-old Caucasian female presented to the emergency department with complaints of back pain and lower-extremity weakness with associated saddle paresthesia. Clinical examination revealed hyporeflexia with a diminished sensation in the left lower extremity. Accurate diagnosis using MRI and a comprehensive clinical approach is vital for early recognition and differentiation of cauda equina syndrome, spinal stenosis, arachnoiditis, spinal abscess, and epidural hematoma. In this case, the initial lumbar MRI demonstrated an empty thecal sac at L4-L5, which can be seen in cases of arachnoiditis and inflammatory arthropathy. With a negative inflammatory lumbar puncture and unresolved symptoms post methylprednisolone treatment, CT myelogram was ordered, which confirmed the presence of a lumbar arachnoid cyst at L4-L5. While arachnoiditis is primarily managed with symptomatic treatment, this patient had a spinal arachnoid cyst, which required surgical intervention to relieve compression and symptoms.

Indexed as

arachnoiditisct myelogramempty thecal saclumbar arachnoid cystlumbar spineneurological diagnosis

Identifiers

PMID41356906
PMCPMC12681182

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