ArticleCureus2025
Pregnancy-Related Acute Kidney Injury in Spontaneous Ovarian Hyperstimulation Syndrome: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Spontaneous ovarian hyperstimulation syndrome (OHSS), a rare entity distinct from iatrogenic forms, presents a diagnostic challenge, particularly in early pregnancy, often leading to delayed recognition and severe systemic complications. We present this case to highlight an unusual and life-threatening presentation of spontaneous OHSS complicated by severe acute kidney injury (AKI) requiring dialysis in early pregnancy, a scenario seldom reported in the literature. A 27-year-old Gravida 2 Para 1 Living 1 (G2P1L1) woman at 10 weeks of spontaneous gestation, with no history of assisted reproductive technology, presented with generalised oedema, reduced urine output, and vaginal bleeding, progressing to multi-organ fluid sequestration, pregnancy loss (missed abortion), and AKI requiring dialysis. Management included aggressive fluid resuscitation, three sessions of hemodialysis for uraemia and severe metabolic acidosis, and therapeutic paracentesis/thoracentesis. Clinicians should maintain a high index of suspicion for OHSS in early gestation with unexplained third spacing and renal dysfunction, and timely fluid management, including renal replacement therapy when indicated.
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