Evidence map›Paper›PMID 41356671›Full record

ArticleFrontiers in artificial intelligence2025

Analysis of article screening and data extraction performance by an AI systematic literature review platform.

Kelsie Cassell, Abiodun Ologunowa, Majid Rastegar-Mojarad, Bianca Chun, Yi-Ling Huang, Dong Wang, Nicole Cossrow

Abstract read
In one paragraph

Article in Frontiers in artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kelsie CassellMerck & Co., Inc., Rahway, NJ, United States.
Abiodun OlogunowaCollege of Pharmacy, University of Rhode Island, Kingston, RI, United States.
Majid Rastegar-MojaradIMO Health, Rosemont, IL, United States.
Bianca ChunMerck & Co., Inc., Rahway, NJ, United States.
Yi-Ling HuangMerck & Co., Inc., Rahway, NJ, United States.
Dong WangMerck & Co., Inc., Rahway, NJ, United States.
Nicole CossrowMerck & Co., Inc., Rahway, NJ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Systematic literature reviews (SLRs) are critical to health research and decision-making but are often time- and labor-intensive. Artificial intelligence (AI) tools like large language models (LLMs) provide a promising way to automate these processes. Methods: We conducted a systematic literature review on the cost-effectiveness of adult pneumococcal vaccination and prospectively assessed the performance of our AI-assisted review platform, Intelligent Systematic Literature Review (ISLaR) 2.0, compared to expert researchers. Results: ISLaR demonstrated high accuracy (0.87 full-text screening; 0.86 data extraction), precision (0.88; 0.86), and sensitivity (0.91; 0.98) in article screening and data extraction tasks, but lower specificity (0.79; 0.42), especially when extracting data from tables. The platform reduced abstract and full-text screening time by over 90% compared to human reviewers. Conclusion: The platform has strong potential to reduce reviewer workload but requires further development.

Indexed as

artificial intelligencedata extractionhealth technology assessmentlarge language modelsreviewer workloadsystematic literature review

Identifiers

PMID41356671
PMCPMC12676488

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.