Evidence map›Paper›PMID 41356670›Full record

ArticleFrontiers in artificial intelligence2025

XAI-BT-EdgeNet: explainable edge-aware deep learning with squeeze-and-excitation for brain tumor detection and prediction.

Deependra Rastogi, Prashant Johri, Massimo Donelli, Tarun Agarwal, Shrikant Tiwari, Pushpa Singh

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Article in Frontiers in artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Deependra RastogiSchool of Computer Science and Engineering, IILM University, Greater Noida, India.
Prashant JohriSchool of Computer Science and Engineering, Galgotias University, Greater Noida, India.
Massimo DonelliDepartment of Civil, Environmental, Mechanical Engineering, University of Trento, Trento, Italy.
Tarun AgarwalDepartment of Computer Science and Engineering, JIIT, Noida, India.
Shrikant TiwariSchool of Computer Science and Engineering, Galgotias University, Greater Noida, India.
Pushpa SinghSchool of Computer Science and Engineering, IILM University, Greater Noida, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Accurate and early detection of brain tumors is critical for effective treatment and improved patient outcomes, yet manual radiological analysis remains time-consuming, subjective, and error-prone. To address these challenges and improve clinical trust in AI systems, this study presents XAI-BT-EdgeNet, an explainable, edge-aware deep learning framework integrated with squeeze-and-excitation (SE) modules for brain tumor detection using MRI scans. Methods: The proposed architecture employs a dual-branch design that fuses high-level semantic features from InceptionV3 with low-level edge representations via an Edge Feature Block, while SE modules adaptively recalibrate feature importance to enhance diagnostic accuracy. To ensure transparency, the model incorporates four XAI techniques-LIME, Grad-CAM, Grad-CAM++, and Vanilla Saliency-which provide interpretable visual justifications for predictions. The framework was trained and evaluated on the Brain Tumor Dataset by Preet Viradiya, comprising 4,589 labeled MRI images divided into Brain Tumor (2,513) and Healthy (2,076) classes. Results: The model achieved 99.58% training accuracy, 99.71% validation accuracy, and 100.00% testing accuracy, alongside minimal loss values of 0.0103, 0.0051, and 0.0026, respectively. These results demonstrate the robustness and precision of the proposed framework in brain tumor classification. Discussion: This work includes the development of a dual-branch CNN architecture that combines semantic and edge features for enhanced classification, the integration of SE modules to highlight clinically significant regions, and the application of multi-method XAI to offer transparent, interpretable outputs for clinical applicability. Overall, XAI-BT-EdgeNet delivers a high-performing, interpretable solution that bridges the gap between deep learning and trustworthy clinical decision-making in brain tumor diagnosis.

Indexed as

brain tumordeep learningedge awareexplainable interpretabilitymagnetic resonance imagingsqueeze and excitation

Identifiers

PMID41356670
PMCPMC12675461

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.