Evidence map›Paper›PMID 41356655›Full record

ArticleClinical case reports2025

Case Report: Omadacycline in the Treatment of Community-Acquired Pneumonia in a Child With Multiple Antimicrobial Allergies.

Ziqi Xu, Wen Pan, Hui Lei, Chen Dong, Biao Zou, Sainan Shu, Wenting Zhang

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ziqi XuDepartment of Pharmacy, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.ORCID https://orcid.org/0009-0008-7117-2762
Wen PanDepartment of Pediatric, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Hui LeiDepartment of Pediatric Ezhou Central Hospital Ezhou China.
Chen DongDepartment of Pediatric, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Biao ZouDepartment of Pediatric, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Sainan ShuDepartment of Pediatric, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Wenting ZhangDepartment of Pharmacy, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omadacycline, a novel once-daily aminomethylcycline antibiotic agent, demonstrates efficacy against prevalent pathogens responsible for community-acquired pneumonia (CAP) in adults. However, the safety and efficacy of omadacycline in younger children have not yet been established. This case report presents a 4-year-old girl with a mixed infection of CAP who exhibited hypersensitivity to multiple antimicrobial agents (piperacillin-tazobactam, ceftazidime, fosfomycin, meropenem, and levofloxacin), was treated with omadacycline followed by doxycycline, and underwent bronchoscopy with bronchoalveolar lavage. The child's condition improved, and no adverse reactions to omadacycline were observed. Potential adverse effects of omadacycline were evaluated, along with its utilization and dosage in children. Omadacycline has the potential to be a viable alternative anti-infective agent for the treatment of pediatric CAP in the absence of other drug options and with adequate safety evaluation and monitoring.

Indexed as

community‐acquired pneumonia (CAP)mixed infectionMycoplasma pneumoniae pneumoniaomadacycline

Identifiers

PMID41356655
PMCPMC12680490

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.