Evidence map›Paper›PMID 41356652›Full record

ArticleClinical case reports2025

Unilateral Extremity Swelling, a Rare Manifestation of Scleredema Adultorum of Buschke in a Child: Case Report.

Shabnam Hajiani Ghotbabadi, Dorna Derakhshan, Rida Rubab Amir, Pooneh Tabibi

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shabnam Hajiani GhotbabadiShiraz University of Medical Sciences Shiraz Iran.ORCID https://orcid.org/0000-0003-2029-4619
Dorna DerakhshanShiraz Nephro-Urology Research Center Shiraz Iran.ORCID https://orcid.org/0000-0003-1266-5539
Rida Rubab AmirShiraz University of Medical Sciences Shiraz Iran.
Pooneh TabibiAlborz University of Medical Sciences Karaj Iran.ORCID https://orcid.org/0000-0002-6513-2413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scleredema adultorum of Bushcke is a rare connective tissue disorder that is characterized by skin thickening that commonly starts from the neck and spreads to the face, shoulders, upper back, abdomen, and in some cases, thighs. The symptoms are generally seen after an infection associated with streptococcus. Atypical clinical manifestations of the disease have been reported in a 13-year-old boy, who developed unilateral lower extremity swelling of the right thigh and leg and was admitted to the hospital with the primary diagnosis of Deep vein thrombosis (DVT). The ultimate diagnosis of scleredema adultorum of Buschke with an uncommon manifestation was established based on the clinical symptoms and ASO titers. This case has been reported to emphasize the importance of the unique signs and symptoms of the disease, leading to uncommon differential diagnosis which requires extensive investigation.

Indexed as

Buschkeconnective tissue disordersDVTedema in childrenextremity swellingScleredema

Identifiers

PMID41356652
PMCPMC12680508

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.