Evidence map›Paper›PMID 41356580›Full record

ArticleWorld journal of cardiology2025

Femoral artery plaque: A simple ultrasound clue for severe coronary stenosis.

Nadezhda G Gumanova, Dmitry K Vasilyev, Alexandre A A Mols, Oxana M Drapkina, Anton R Kiselev

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Article in World journal of cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Nadezhda G GumanovaCoordinating Center for Fundamental Research, National Medical Research Center for Therapy and Preventive Medicine, Moscow 101990, Russia.
Dmitry K VasilyevDepartment of Cardiovascular X-ray Surgery, National Medical Research Center for Therapy and Preventive Medicine, Moscow 101990, Russia.
Alexandre A A MolsCoordinating Center for Fundamental Research, National Medical Research Center for Therapy and Preventive Medicine, Moscow 101990, Russia.
Oxana M DrapkinaDepartment of Fundamental and Applied Aspects of Obesity, National Medical Research Center for Therapy and Preventive Medicine, Moscow 101990, Russia.
Anton R KiselevCoordinating Center for Fundamental Research, National Medical Research Center for Therapy and Preventive Medicine, Moscow 101990, Russia. antonkis@list.ru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith rising angiography costs and risks, we explored whether a 5-minute femoral ultrasound can predict patients that actually require angiography.

aimTo detect associations between atherosclerosis of peripheral arteries and coronary stenosis in patients with coronary heart disease (CHD).

methodsThe study included a total of 218 patients (63 ± 10.9 years of age; 54% male) with CHD subjected to coronary angiography and routine diagnostic assessment, including ultrasound imaging to assess the extent of peripheral atherosclerotic lesions. Receiver operating characteristic analysis and binomial logistic regression were used to detect the associations.

resultsWe demonstrated for the first time that the presence of atherosclerotic plaque with ≥ 70% stenosis in femoral arteries was associated with significant coronary stenosis, with 93% sensitivity and 90% specificity, and thus can be used as an additional diagnostic marker for coronary stenosis. The data indicated associations between femoral artery atherosclerosis and atherosclerotic lesions of coronary arteries, with a high correlation coefficient

conclusionFor resource-limited clinics, our findings suggest skipping carotids - femoral ultrasound alone may suffice to rule out severe CHD. Ultrasound imaging femoral artery atherosclerosis provides a simplified approach for patient stratification.

Indexed as

AtherosclerosisCoronary heart diseaseCoronary stenosisDiagnostic testFemoral plaquesGensini scorePeripheral atherosclerosisUltrasound

Identifiers

PMID41356580
PMCPMC12678886

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