SynthesisClinics in orthopedic surgery2025
Total Hip or Knee Arthroplasty in Patients with a History of Native Joint Septic Arthritis: A Meta-analysis and Systematic Review of Risk Factors of Prosthetic Joint Infection.
Synthesis in Clinics in orthopedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Septic arthritis is a debilitating diagnosis, and many of these patients elect to undergo total knee arthroplasty (TKA) and total hip arthroplasty (THA). The purpose of this systematic review and meta-analysis is to assess the risk of prosthetic joint infection (PJI) in those who undergo primary TKA or THA with a history of septic joint arthritis. Secondarily, we will evaluate patient-specific or surgical factors that could increase the risk of primary arthroplasty failure. Methods: A comprehensive search of PubMed, CINAHL Plus, Embase, and Scopus was performed. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed for study selection, data extraction, and analysis. From a total of 404 articles, 18 studies were selected for inclusion. Results: Our final cohort consisted of 1,758 arthroplasties with Conclusions: Male sex and resistant organism as causes of septic arthritis were associated with an increased risk of PJI in patients with a history of native septic arthritis. Single- and 2-stage procedures had similar success rates. Future studies should be larger and focus on long-term outcomes in these patients.
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