Evidence map›Paper›PMID 41356519›Full record

ArticleWorld journal of gastroenterology2025

Covering the biopsy hole check valve with "enzymolysis gauze" reduces bacterial contamination in the endoscopy room.

Hu-Bin Xia, Ying-Dong Hou, Yuan Zhang, Ai-Yu Yu, Qi Ding, Wen-Li Ruan, Yi-Shen Mao, Shu-Jiong Feng, Cong Ding, Yi-Feng Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hu-Bin XiaThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou 310000, Zhejiang Province, China.
Ying-Dong HouDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China.
Yuan ZhangDepartment of Gastroenterology, The Second People's Hospital of Fuyang District, Hangzhou 310000, Zhejiang Province, China.
Ai-Yu YuDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China.
Qi DingDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China.
Wen-Li RuanDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China.
Yi-Shen MaoDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China.
Shu-Jiong FengDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China.
Cong DingDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China.
Yi-Feng ZhouDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBacterial contamination during colonoscopy is a significant concern, yet few studies have evaluated bacterial aerosols. This study aimed to determine whether covering the biopsy hole check valve with enzymolysis gauze (refers to sterile gauze soaked in a multi-enzyme cleaning solution) reduces bacterial air pollution in endoscopy rooms.

aimTo evaluate the efficacy of an enzymolysis gauze cover in reducing bacterial aerosols from the biopsy valve.

methodsThis prospective, single-blind trial included 80 patients undergoing elective diagnostic colonoscopy. During the procedure, the biopsy hole check valve was either covered or left uncovered with enzymolysis gauze. Air samples (100 L) were collected at a distance of 30 cm from the biopsy hole check valve and approximately 140 cm above the floor using a percussive air sampling instrument. Gram-positive bacteria were cultured on standard 90 mm colimycin nalidixic agar blood plates. The primary outcome measures were bacterial load and species identification.

resultsCovering the biopsy hole check valve with enzymolysis gauze reduced bacterial load near the check valve from 50 colony-forming unit (CFU)/m

conclusionApplying enzymolysis gauze to cover the biopsy hole check valve significantly reduces bacterial aerosol contamination in endoscopy rooms during colonoscopy.

Indexed as

Air MicrobiologyColonoscopyEquipment ContaminationAdultAerosolsAgedBacterial LoadBiopsyFemaleHumansMaleMiddle AgedPatients' RoomsProspective StudiesSingle-Blind MethodAerosolsAerosolBacterial contaminationBiopsy hole check valveColonoscopeEndoscopyEnteric bacterial microfloraEnzymolysis gauzeInfection

Identifiers

PMID41356519
PMCPMC12678970

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.