Evidence map›Paper›PMID 41356463›Full record

ArticleJID innovations : skin science from molecules to population health2025

Characterization of Malignant Adnexal Tumors of the Head and Neck by Targeted Analysis of Cancer Genes and Human Papillomavirus 42.

Eleanor Dowell, Ruchika Mahapatra, Justin Bishop, Andrew Matsumoto, Alexandra Callan, Travis W Vandergriff, Aya Alame, Greg Hosler, Jeffrey Gagan, Rajiv I Nijhawan and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eleanor DowellMedical School, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Ruchika MahapatraMedical School, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Justin BishopDepartment of Pathology, The University of Texas Southwestern Medical Center, Dallas, Texas.
Andrew MatsumotoDepartment of Dermatology, University of New Mexico, Albuquerque, New Mexico, USA.
Alexandra CallanDepartment of Orthopedic Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Travis W VandergriffDepartment of Pathology, The University of Texas Southwestern Medical Center, Dallas, Texas.
Aya AlameMedical School, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Greg HoslerMedical School, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jeffrey GaganLaboratory of Pathology, National Cancer Institute, Bethesda, Maryland, USA.
Rajiv I NijhawanDepartment of Dermatology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Richard C WangDepartment of Dermatology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant adnexal tumors of the head and neck, including syringoid eccrine carcinoma and microcystic adnexal carcinoma, are rare tumors that are thought to arise in adnexal epithelium. The etiopathogenesis of these tumors is poorly understood, and the precise classification of these tumors can be challenging. Human papillomavirus 42 (HPV42) promotes the development of digital papillary adenocarcinoma, a rare adnexal tumor of the extremities and genital skin. Malignant adnexal tumors of the head and neck were assessed through targeted RNA sequencing of the cancer exome and specific RT-PCR for HPV42. Of the 9 cases identified, 7 yielded RNA of sufficient quality for RNA sequencing. Unexpectedly, these analyses revealed a

Indexed as

Cancer exomeDigital papillary adenocarcinomaHPV42Microcystic adnexal carcinomaSyringoid eccrine carcinoma

Identifiers

PMID41356463
PMCPMC12675143

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.