Evidence map›Paper›PMID 41356453›Full record

ArticleACS organic & inorganic Au2025

Guest-Induced Conformational Switching in "One Wall" Calix[4]pyrrole Cavitands Functionalized with an Inwardly Directed Carboxylic Acid.

Mingkai Zhao, Andrés F Sierra, Gemma Aragay, Pablo Ballester

Abstract read
In one paragraph

Article in ACS organic & inorganic Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mingkai ZhaoInstitute of Chemical Research of Catalonia (ICIQ-CERCA), The Barcelona Institute of Science and Technology (BIST), Av. Països Catalans, 16, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0003-4058-3805
Andrés F SierraInstitute of Chemical Research of Catalonia (ICIQ-CERCA), The Barcelona Institute of Science and Technology (BIST), Av. Països Catalans, 16, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0002-1940-0886
Gemma AragayInstitute of Chemical Research of Catalonia (ICIQ-CERCA), The Barcelona Institute of Science and Technology (BIST), Av. Països Catalans, 16, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0002-2405-0278
Pablo BallesterInstitute of Chemical Research of Catalonia (ICIQ-CERCA), The Barcelona Institute of Science and Technology (BIST), Av. Països Catalans, 16, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0001-8377-6610

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the design, synthesis, and conformational analysis of two aryl-extended calix[4]-pyrrole (AE-C[4]-P) cavitands that feature a single methylene bridge and an opposed aromatic bridging wall with an inward-facing carboxylic acid. Inspired by Rebek's introverted acid motif, these cavitands were developed to explore guest-induced conformational switching between "equatorial" and "axial" orientations of the bridging aromatic wall. Binding studies with

Indexed as

aryl-extended calix[4]pyrrolescavitandsconformational switchingN-oxide bindingstimuli-responsive hosts

Identifiers

PMID41356453
PMCPMC12679308

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.