Evidence map›Paper›PMID 41356420›Full record

ArticleMaterials today. Bio2025

Low-dose ionizing radiation

Filipe Rocha, Inês Sofia Vala, Paula de Oliveira, Pedro Faísca, Carolina Fernandes, Marta Teixeira Pinto, Filomena Pina, Esmeralda Poli, Isabel Diegues, Eugénia Carvalho and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Filipe RochaCentro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Portugal.
Inês Sofia ValaCentro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Portugal.
Paula de OliveiraCentro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Portugal.
Pedro FaíscaGulbenkian Institute for Molecular Medicine, Oeiras, Portugal.
Carolina FernandesCentro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Portugal.
Marta Teixeira Pintoi3s - Institute for Research and Innovation in Health, University of Porto, Portugal.
Filomena PinaHospital Santa Maria, Unidade Local de Saúde Santa Maria (ULSSM), Portugal.
Esmeralda PoliHospital Santa Maria, Unidade Local de Saúde Santa Maria (ULSSM), Portugal.
Isabel DieguesHospital Santa Maria, Unidade Local de Saúde Santa Maria (ULSSM), Portugal.
Eugénia CarvalhoCNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra. CIBB - Center for Inovative Biomedicine and Biotechnology, Institute for Interdisciplinary Research, University of Coimbra, Portugal.
Cristina C Barriasi3s - Institute for Research and Innovation in Health, University of Porto, Portugal.
Susana Constantino Rosa SantosCentro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds (CWs), particularly in diabetic patients, remain a major clinical challenge because of impaired angiogenesis and fibroblast dysfunction. This study investigated the therapeutic synergy between low-dose ionizing radiation (LDIR; 0.3 Gy) and prevascularized spheroids composed of human dermal fibroblasts (HDFs) and endothelial colony-forming cells (ECFCs) embedded in a xeno-free fibrin hydrogel.

Indexed as

AngiogenesisChronic woundsEndothelial cellsFibroblastsLow-dose ionizing radiationSpheroidsWound healing

Identifiers

PMID41356420
PMCPMC12676115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.