Evidence map›Paper›PMID 41356365›Full record

ArticleResearch square2025

Genomic insights into the spread and evolution of insecticide resistance in Anopheles gambiae s.l. from Burkina Faso.

Mahamadi Kientega, Honorine Kaboré, Grégoire Sawadogo, Tin-Yu J Hui, Nouhoun Traoré, Abdoul-Azize Millogo, Hamidou Maiga, Alistair Miles, Chris S Clarkson, Abdoulaye Diabaté

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PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Mahamadi KientegaInstitut de Recherche en Sciences de la Santé.
Honorine KaboréInstitut de Recherche en Sciences de la Santé.
Grégoire SawadogoInstitut de Recherche en Sciences de la Santé.
Tin-Yu J HuiImperial College London.
Nouhoun TraoréInstitut de Recherche en Sciences de la Santé.
Abdoul-Azize MillogoInstitut de Recherche en Sciences de la Santé.
Hamidou MaigaInstitut de Recherche en Sciences de la Santé.
Alistair MilesEllison Institute of technology.
Chris S ClarksonWellcome Sanger Institute.
Abdoulaye DiabatéInstitut de Recherche en Sciences de la Santé.

Funding

Genome-based diagnostics for monitoring and evaluation of insecticide resistance in Anopheles gambiaeR01AI116811 · NIAID · TMLIVERPOOL SCHOOL OF TROPICAL MEDICINE · PI Martin James Donnelly · 2016 to 2026
$4.6M
Gates Foundation INV-001927Gates Foundation INV-031595NIAID NIH HHS R01 AI116811Wellcome Trust
6 · The paper itself

Abstract

Background: The intensive use of insecticide-based control tools has led to the rapid evolution of resistant phenotypes in malaria vector populations. Understanding the evolutionary processes underlying these resistances is essential to inform the development and deployment of effective control interventions. This study investigated the geographical spread and the genetic background of insecticide resistance variants in Burkina Faso. Results: The study identified five pyrethroid-resistant mutations ( Conclusion: The study underscores the extent and spreads of insecticide resistance variants in Burkina Faso. It highlights the importance of genomic surveillance of malaria vectors to monitor and detect new resistance variants and to understand the evolutionary processes in vector populations.

Indexed as

An. gambiae s.l.genomicsinsecticidemalariaresistance

Identifiers

PMID41356365
PMCPMC12676430

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.