ArticleFrontiers in neurology2025
Efficacy analysis of percutaneous balloon compression therapy for trigeminal neuralgia guided by three-dimensional digital subtraction angiography navigation.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: The aim of this study was to evaluate the clinical efficacy of percutaneous microballoon compression guided by three-dimensional digital subtraction angiography (DSA) navigation in treating primary trigeminal neuralgia. Methods: We retrospectively analyzed 40 patients with primary trigeminal neuralgia who underwent percutaneous microballoon compression under three-dimensional digital subtraction angiography navigation between January 2019 and April 2025. Post-operative pain relief was assessed 1 d, 1 month, and 3 months post-surgery. Results: All 40 patients underwent three-dimensional digital subtraction angiography dual-volume imaging and 3D-Dyna-computed tomography cranial reconstruction at the pre-puncture, needle placement, balloon positioning, and balloon inflation stages. We adjusted the balloon morphology during inflation, considering cranial reconstruction and balloon positioning, for optimization. Post-operatively, all patients showed significant pain relief: 38 achieved immediate pain resolution, one resolved at 3 days, and one at 2 weeks. Overall, all 40 patients developed facial numbness, two developed perioral herpes, one developed diplopia, and one experienced transient masseter muscle weakness; all these resolved with treatment. Two patients showed recurrence during follow-up. Discussion: Three-dimensional digital subtraction angiography navigation-guided percutaneous microballoon compression is a safe and minimally invasive technique for the treatment of trigeminal neuralgia. Real-time 3D-Dyna-computed tomography reconstruction enables the visualization of the balloon-petrous apex relationship, enhancing procedural precision and therapeutic outcomes.
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