Evidence map›Paper›PMID 41356235›Full record

ArticleFrontiers in aging neuroscience2025

Is cognitive reserve associated with cognitive function across stroke severity? A longitudinal study among Chinese stroke patients.

Yinuo Ou, Yanrong Zhang, Yalin Lv, Silian Ding, Xiangjing Kong, Hanzhang Xu, Bei Wu, Hui Wei, Juan Li

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Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Yinuo OuDepartment of Nursing, Huashan Hospital, Fudan University, Shanghai, China.
Yanrong Zhang *Department of Nursing, Huashan Hospital, Fudan University, Shanghai, China.
Yalin Lv *Department of Nursing, Huashan Hospital, Fudan University, Shanghai, China.
Silian DingShanghai Fourth People's Hospital affiliated to Tongji University, Shanghai, China.
Xiangjing KongAir Force Hospital of Eastern Theater Command, Nanjing, China.
Hanzhang XuSchool of Nursing, Duke University, Durham, NC, United States.
Bei WuRory Meyers College of Nursing, New York University, New York, NY, Unites States.
Hui WeiDepartment of Nursing, Huashan Hospital, Fudan University, Shanghai, China.
Juan LiDepartment of Nursing, Huashan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cognitive decline is common after stroke. This study assessed the longitudinal associations between cognitive reserve and post-stroke cognitive function and tested whether these associations differ across patients' stroke severity. Methods: A longitudinal survey was conducted among 371 patients with acute ischemic stroke from four stroke centers in China from 2022 to 2023. Eligible patients were recruited at acute stage and followed up at 3 and 6 months after onset. Cognitive reserve was assessed by Cognitive Reserve Index questionnaire within 7 days after stroke onset. Cognitive function was assessed by Montreal Cognitive Assessment, Changsha Version at each time point. Stroke severity was assessed using the National Institutes of Health Stroke Scale at admission. Linear mixed models were applied to assess associations between cognitive reserve and cognitive function across stroke severity. Results: Among stroke survivors, cognitive function improved over time after the onset ( Conclusion: Cognitive reserve can potentially mitigate the impact of stroke on long-term cognitive decline in Chinese patients with acute ischemic stroke. Targeting cognitive reserve may be a viable strategy to prevent or slow post-stroke cognitive decline. The study supports a more nuanced assessment of cognitive reserve as a standard in clinical studies.

Indexed as

acute ischemic strokecognitive reservelongitudinal studypost stroke cognitive impairmentstroke severity

Identifiers

PMID41356235
PMCPMC12676486

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.