ArticleFood science & nutrition2025
Protective Effects of Resveratrol on Heat Stress-Induced Liver Dysfunction in Broilers Through Modulating Autophagy and NLRP3 Inflammasome.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A flavonoid extract from Bupleurum aerial parts given at recovery onset attenuates residual liver and lung injury in yellow-feathered broilers after acute heat exposure.Poultry science · 2026Article
- Protective Effects of Resveratrol on Heat Stress-Induced Liver Dysfunction in Broilers Through Modulating Autophagy and NLRP3 Inflammasome.Food science & nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aims to explore the effects of resveratrol on the NLRP3 inflammasome and its regulatory mechanism in the liver of heat-stressed broilers. Broilers were randomly divided into three groups: (1) Control (23°C ± 2°C), (2) Heat stress (HS, 35°C ± 2°C, 8 h/day), and (3) Resveratrol (HS + resveratrol) group. Resveratrol supplementation (400 mg/kg diet) commenced 48 h prior to HS and continued throughout the experimental period. The results showed that resveratrol improved growth performance with a higher average daily gain (ADG) and lower feed conversion ratio (FCR), and increased liver weight and index along with reduced inflammatory cell infiltration in broilers. In addition, resveratrol upregulated the autophagy-related genes and protein levels in the liver. Moreover, resveratrol obviously down-regulated the protein and mRNA levels of the NOD-like receptor protein 3 (NLRP3) inflammasome. In conclusion, resveratrol mitigated heat stress-induced liver injury by modulating autophagy and down-regulating NLRP3 inflammasome activation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.