Evidence map›Paper›PMID 41356080›Full record

ArticleWorld journal of clinical cases2025

Recurrent hemoptysis after laryngectomy-acquired hemophilia induced by laryngeal cancer surgery and chemoradiotherapy: A case report.

Peng-Wei Zhao, Yan-Sheng Hu, Zheng Jiang, Mailudan Ainiwaer, Jun Liu, Fei Chen

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peng-Wei ZhaoDepartment of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610048, Sichuan Province, China.
Yan-Sheng HuDepartment of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610048, Sichuan Province, China.
Zheng JiangDepartment of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610048, Sichuan Province, China.
Mailudan AiniwaerDepartment of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610048, Sichuan Province, China.
Jun LiuDepartment of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610048, Sichuan Province, China.
Fei ChenDepartment of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610048, Sichuan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcquired hemophilia A (AHA) is a rare autoimmune bleeding disorder characterized by autoantibodies against coagulation factor VIII (FVIII), leading to spontaneous bleeding in patients without a personal or family history of bleeding disorders. While AHA has been reported in association with various cancers, this case represents, to our knowledge, the first reported instance of AHA following head and neck cancer surgery and subsequent chemoradiotherapy. CASE SUMMARY: We present the case of a 65-year-old male with a history of hypopharyngeal squamous cell carcinoma (T4bN2cM0, AJCC 8

conclusionThis case underscores vigilance for AHA after head and neck cancer therapy to enable prompt treatment.

Indexed as

Acquired hemophilia ACase reportChemoradiotherapyHypopharyngeal squamous cell carcinomaImmunosuppressive therapyParaneoplastic syndromeSurgery

Identifiers

PMID41356080
PMCPMC12678933

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