Evidence map›Paper›PMID 41356009›Full record

ArticleFrontiers in endocrinology2025

Clinical impact of progesterone levels on HCG trigger day in a follicular long-term IVF protocol.

Xiao Han, Na Song, Ya Zhang, Jingjing Wang, Fang Zhao, Yanping Zhang, Zhanrong Shi, Yuzhen Lv, Menglan Wu, Fang Yuan and 1 more

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiao HanReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Na SongReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Ya ZhangReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Jingjing WangReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Fang ZhaoReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Yanping ZhangReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Zhanrong ShiReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Yuzhen LvReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Menglan WuReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Fang YuanReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.
Guangli ZhuReproductive Medicine Center, Jiaozuo Women's and Children's Hospital, Jiaozuo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have shown that elevated progesterone (P4) levels on human chorionic gonadotropin (HCG) trigger days may affect endometrial tolerance. However, no standardized threshold has been established for the impact of late follicular phase P4 on clinical outcomes. This study aimed to assess the influence of P4 levels on the day of HCG trigger in a follicular long-term protocol on clinical outcome. Methods: This retrospective study analyzed 889 fresh Results: A significant correlation was identified between the P4 level and both the clinical pregnancy rate ([CPR] OR: 0.54, 95% CI: 0.37 - 0.81, Conclusions: In blastocyst transfer cycles, the P4 level on the HCG trigger day shows a curvilinear association with the outcomes of pregnancy. The optimal threshold was found to be as 1.0 ng/mL.

Indexed as

Chorionic GonadotropinFertilization in VitroFollicular PhaseOvulation InductionProgesteroneAdultEmbryo TransferFemaleHumansPregnancyPregnancy RateRetrospective StudiesChorionic GonadotropinProgesteroneclinical pregnancyfollicular long-term protocolfresh embryo transferHCG trigger dayprogesterone

Identifiers

PMID41356009
PMCPMC12675159

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.