Evidence map›Paper›PMID 41355992›Full record

ReviewFrontiers in cellular and infection microbiology2025

The role of long non-coding RNAs and circular RNAs in immune evasion of influenza A virus: recent advances.

Yanghua Ju, Yanchun Li, Chenxu Zhou, Xiuhua Yu

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yanghua Ju *Department of Pediatric Respiration, Children's Medical Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Yanchun Li *Department of Pediatric Respiration, Children's Medical Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Chenxu ZhouDepartment of Pediatric Respiration, Children's Medical Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Xiuhua YuDepartment of Pediatric Respiration, Children's Medical Center, The First Hospital of Jilin University, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The capacity of influenza A virus (IAV) to circumvent immune defenses in hosts renders it a persistent major peril to worldwide public health. Investigations conducted lately underscore the vital functions played by circular RNAs (circRNAs) and long non-coding RNAs (lncRNAs) during interactions between viruses and their hosts. This review summarizes current understanding of how lncRNAs and circRNAs participate in IAV immune evasion by regulating antiviral signaling pathways, interfering with interferon responses, modulating inflammatory cytokine production and cell metabolism, and affecting viral replication. This review examines molecular actions exhibited by particular lncRNAs and circRNAs within such interactions, assesses their suitability for therapeutic targets and diagnostic biomarkers, and outlines avenues for subsequent investigations across this fast-developing domain.

Indexed as

Host-Pathogen InteractionsImmune EvasionInfluenza A virusInfluenza, HumanRNA, CircularRNA, Long NoncodingAnimalsCytokinesHumansInterferonsSignal TransductionVirus ReplicationCytokinesInterferonsRNA, CircularRNA, Long Noncodingantiviral responsecircular RNAimmune evasioninfluenza A viruslong non-coding RNA

Identifiers

PMID41355992
PMCPMC12678386

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.