Evidence map›Paper›PMID 41355963›Full record

ArticleTheranostics2026

Super-enhancer-driven core transcription factor FOXP1 delays endothelial cell senescence via phase separation-mediated SESN3 activation.

Lushuang Mao, Zhao-Fu Liao, Dong Tang, Yumin Qiu, Min Yang, Yanshang Li, Yituan Xie, Weimin Feng, Ze-Jun Zheng, Xiao-Meng Liu and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Transcriptional regulation in cardiovascular aging.Frontiers in cardiovascular medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Lushuang MaoGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Zhao-Fu LiaoGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Dong TangGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Yumin QiuDepartment of Hypertension and Vascular Disease, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.
Min YangDepartment of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, P.R. China.
Yanshang LiDepartment of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, P.R. China.
Yituan XieDepartment of Neurosurgery, the Affiliated Huizhou First Hospital, Guangdong Medical University, Huizhou, Guangdong 516003, P.R. China.
Weimin FengInstitute of Biochemistry & Molecular Biology, School of Basic Medical Sciences, Guangdong Medical University, Dongguan, P.R. China.
Ze-Jun ZhengInstitute of Biochemistry & Molecular Biology, School of Basic Medical Sciences, Guangdong Medical University, Dongguan, P.R. China.
Xiao-Meng LiuGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Jing-Ru YeGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Shui-Hong LuGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Xin-Bin TangGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Ming ShiGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Yun-Fei QuCardiovascular Center, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, P.R. China.
Heng LiDepartment of Cardiovascularology, Dongguan Tungwah Hospital, Dongguan, 523808, P.R. China.
Zhu-Guo WuCardiovascular Center, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, P.R. China.
Shun XuGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Xinguang LiuGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.
Junjun DingRNA Biomedical Institute, Sun Yat-Sen Memorial Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, P.R. China.
Jian-Jun XieInstitute of Biochemistry & Molecular Biology, School of Basic Medical Sciences, Guangdong Medical University, Dongguan, P.R. China.
Jun TaoDepartment of Hypertension and Vascular Disease, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.
Xing-Dong XiongGuangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cellular SenescenceEndothelial CellsForkhead Transcription FactorsRepressor ProteinsChromatinEpigenesis, GeneticHistonesHumansHuman Umbilical Vein Endothelial CellsPhase SeparationChromatinForkhead Transcription FactorsFOXP1 protein, humanHistonesRepressor Proteinsendothelial cell senescenceepigenetic regulationFOXP1liquid-liquid phase separationsuper-enhancer

Identifiers

PMID41355963
PMCPMC12679572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.