Evidence map›Paper›PMID 41355928›Full record

ArticleSexual medicine2025

Awareness, use, and acceptability of HIV pre-exposure prophylaxis and post-exposure prophylaxis among men who have sex with men: evidence from China.

Zhujun Lian, Xingliang Zhang, Junfang Xu

Abstract read
In one paragraph

Article in Sexual medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhujun LianSchool of Public Health, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China.
Xingliang ZhangHangzhou Center for Disease Control and Prevention (Hangzhou Health Supervision Institution), Hangzhou 310000, China.
Junfang XuSchool of Public Health, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China.ORCID https://orcid.org/0000-0001-9133-8960

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Men who have sex with men (MSM) represent a high-incidence population with HIV, while HIV pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) are among the most effective interventions to prevent HIV transmission and save lives. Aim: This study aims to analyze the awareness, use, and acceptability of HIV PrEP and PEP among MSM to inform optimized implementation strategies for this population. Methods: A non-government organization based questionnaire survey was used to collect data from July 2022 to December 2023. A total of 1065 MSM were incorporated into our analysis with the following information: socio-demographics, awareness, use, and acceptability of HIV PrEP and PEP. Binary logistic regression analysis was employed to determine the factors on seeking, use, and acceptability of PrEP and PEP. Outcomes: Despite high awareness of PrEP/PEP, actual adoption remained limited among MSM. Results: The average age of the participants was 28.48 ± 7.33. About 89.7% of the participants were aware of PrEP and 94.4% were aware of PEP. About 7.9% of the participants have used PrEP and 11.6% have used PEP. About 87.9% of the participants had willingness to use PrEP and 90.2% had willingness to use PEP. The main ways for the participants to get PrEP and PEP were through Internet hospitals, followed by local hospitals, and recommendations from acquaintances. The most concerned factors were preventive effect followed by side effects of PrEP and PEP. Doubts about the preventive effect of PrEP and PEP significantly affect their seeking, use, and acceptability ( Clinical Translation: This study provides insights for enhancing the implementation of HIV PrEP and PEP among MSM. Strengths and Limitations: This study is the first to depict the situation of awareness, use, and acceptability of HIV PrEP and PEP among MSM in China. Limitations involve social desirability bias and reliance on self-reported diagnosis. Conclusion: Accelerating PrEP/PEP scale-up requires enhanced risk perception, expanded service access, and comprehensive sensitization programs.

Indexed as

ChinaHIVMSMpost-exposure prophylaxispre-exposure prophylaxis

Identifiers

PMID41355928
PMCPMC12676726

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.