ArticleJournal of surgical case reports2025
Squamous cell carcinoma of the sigmoid colon: a rare case report.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Squamous cell carcinoma (SCC) of the colorectum is rare malignancy. It constitutes only 0.1-0.25 per 1000 cases of colorectal carcinoma. Here, we report a rare case of primary SCC of the sigmoid colon in a 40-year-old female from Western Uttar Pradesh, India. She presented with acute intestinal obstruction and a history of altered bowel habits and decreased appetite. Surgical resection revealed a constricted tumor in the sigmoid colon. Histopathological analysis confirmed the diagnosis of SCC with no lymph node involvement (0/32). The patient received four cycles of adjuvant chemotherapy (FOLFOX regimen) and has remained disease-free during a 3-year follow-up. Given its rarity, there is no established treatment protocol for colorectal SCC. Surgical resection remains the mainstay of treatment, with uncertain benefits from chemotherapy or radiotherapy. Early diagnosis and long-term follow-up are crucial for favorable outcomes in such uncommon presentations.
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