Evidence map›Paper›PMID 41355829›Full record

ReviewWorld journal of orthopedics2025

Internal diseases and molecular mechanisms causing slipped capital femoral epiphysis in children.

Yi-Fan Chen, Ke Ning, Yu-Yin Xie, Can Liu, Yi-Tong Ding, Zhong-Wen Tang, Jie Wen, Sheng Xiao, Yu-Fei Li

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of orthopedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yi-Fan ChenDepartment of Pediatric Orthopedics, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410013, Hunan Province, China.
Ke NingDepartment of Anatomy, Hunan Normal University, Changsha 410013, Hunan Province, China.
Yu-Yin XieDepartment of Pediatric Orthopedics, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410013, Hunan Province, China.
Can LiuDepartment of Anatomy, Hunan Normal University, Changsha 410013, Hunan Province, China.
Yi-Tong DingDepartment of Anatomy, Hunan Normal University, Changsha 410013, Hunan Province, China.
Zhong-Wen TangDepartment of Pediatric Orthopedics, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410013, Hunan Province, China.
Jie WenDepartment of Pediatric Orthopedics, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410013, Hunan Province, China. cashwj@qq.com.
Sheng XiaoDepartment of Pediatric Orthopedics, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410013, Hunan Province, China.
Yu-Fei LiDepartment of Anatomy, Hunan Normal University, Changsha 410013, Hunan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Slipped capital femoral epiphysis (SCFE) is a hip disorder that predominantly affects adolescents. The primary pathological change involves the displacement of the femoral head epiphysis from its normal position at the growth plate toward the metaphysis of the femoral neck. This condition can result in hip pain, abnormal gait, and even avascular necrosis of the femoral head, significantly impacting the quality of life in adolescents. Currently, the exact etiology of SCFE remains unclear; however, evidence suggests that risk factors include endocrine disorders, metabolic conditions, and genetic diseases. Endocrine disorders encompass hypothyroidism, growth hormone abnormalities, hypogonadism, and obesity-related hormonal imbalances. Metabolic conditions involve obesity, vitamin D deficiency or rickets, and renal osteodystrophy. Genetic diseases include mutations in the

Indexed as

Growth hormone abnormalitiesHypogonadismHypothyroidismObesity-related hormonal imbalancesSlipped capital femoral epiphysis

Identifiers

PMID41355829
PMCPMC12679099

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.