Evidence map›Paper›PMID 41355824›Full record

ReviewWorld journal of orthopedics2025

Prophylactic fixation in elderly fractures: Preventive breakthrough or unnecessary intervention?

Mohamed Sameer, Sathish Muthu, Srujun Vadranapu

Abstract readReview
In one paragraph

Review in World journal of orthopedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mohamed SameerDepartment of Orthopaedics, Sri Ramachandra Institute of Higher Education and Research, Chennai 600116, Tamil Nādu, India.
Sathish MuthuCentral Research Laboratory, Meenakshi Medical College Hospital and Research Institute, Meenakshi Academy of Higher Education and Research, Kanchipuram 631552, Tamil Nadu, India.
Srujun VadranapuDepartment of Orthopaedics, Royal Care Super Speciality Hospital, Coimbatore 641062, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prophylactic fixation (ProFix) of the proximal femur in elderly patients with osteoporosis presents a forward-thinking approach to preventing debilitating fractures and their associated complications. By addressing fracture risk before an injury occurs, ProFix has the potential to enhance patient outcomes, promote long-term mobility, and reduce healthcare costs. Early intervention in individuals at high risk can significantly lower hospital admissions, shorten recovery periods, and preserve independence, mitigating challenges such as chronic pain and reduced life expectancy. Given the high prevalence of undiagnosed osteoporosis, prioritising early risk assessment and targeted prevention is essential. Advancements in minimally invasive surgical techniques and safer anaesthesia methods further support ProFix as a feasible and effective strategy to decrease fracture-related morbidity, improve overall patient well-being, and optimise the use of healthcare resources. This opinion review details the evidence supporting this concept, its efficacy, the challenges in its implementation, and a strategic plan for future implementation.

Indexed as

Bone healthElderly patientsFracture preventionOsteoporotic fracturesPredictive analyticsProphylactic fixationProximal femur

Identifiers

PMID41355824
PMCPMC12679079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.