Evidence map›Paper›PMID 41355206›Full record

ArticleThe journal of vascular access2026

Addressing infection in totally implantable venous access ports: An ex vivo study on bacterial transfer and the Forsvall Port needle design.

Håkan Pärsson, Magnus Wagenius, Maria Utter, Jonas Tverring, José Francisco Pereira Cardoso, Andreas Forsvall

Abstract readComparative Study
In one paragraph

Article in The journal of vascular access, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Håkan PärssonDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0002-6566-8381
Magnus WageniusFaculty of Medicine, Department of Clinical Sciences, Infection Medicine, Lund University, Lund, Sweden.ORCID 0000-0002-4004-269X
Maria UtterFaculty of Medicine, Department of Clinical Sciences, Infection Medicine, Lund University, Lund, Sweden.ORCID 0009-0002-4486-6810
Jonas TverringFaculty of Medicine, Department of Clinical Sciences, Infection Medicine, Lund University, Lund, Sweden.ORCID 0000-0003-0939-6673
José Francisco Pereira CardosoFaculty of Medicine, Department of Dermatology and Venereology, Lund University, Lund, Sweden.ORCID 0000-0002-6201-3996
Andreas ForsvallFaculty of Medicine, Department of Clinical Sciences, Infection Medicine, Lund University, Lund, Sweden.ORCID 0000-0001-8597-0580

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTotally implantable venous access ports (TIVAPs) are essential for administering chemotherapeutic drugs and nutritional support, but carry a risk of infectious complications. We hypothesized that the design of the current port needle (Huber) could facilitate the collection of bacteria from the skin during puncture, potentially introducing them into TIVAPs and causing infections. This study examines bacterial transfer via needles during TIVAP access and proposes a novel needle design to reduce the risk of infection.

methodsA novel needle, the Forsvall Port needle, was developed with a closed tip to reduce bacterial transmission inside the needle during tissue and port penetration. In a randomized ex vivo setting, human skin samples covered in physiological levels of

resultsThe Forsvall Port needle reduced average bacterial transfer by 87.0% (95% CI: 77.8%-92.4%,

conclusionThe Forsvall Port needle significantly reduces bacterial transfer into TIVAPs, which could potentially decrease TIVAP-related infections. This study demonstrates a strong association between needle design and bacterial transfer during TIVAP access.

Indexed as

Catheterization, Central VenousCatheter-Related InfectionsCatheters, IndwellingCentral Venous CathetersEquipment ContaminationNeedlesSkinStaphylococcal InfectionsStaphylococcus aureusEquipment DesignHumansPuncturesbacterial transfercatheter-related blood stream infectionCRBSIex vivo studyForsvall Port needleHuber needleinfection preventionsubcutaneous venous portTIVAP

Identifiers

PMID41355206
PMCPMC13135649

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.