Evidence map›Paper›PMID 41355180›Full record

ArticleJournal of the American Chemical Society2025

π-Extended Ru-COUBPY Photosensitizers for

Diego Abad-Montero, Eduardo Izquierdo-García, Pierre Mesdom, Albert Gandioso, Elena de la Torre-Rubio, Manel Bosch, Juan Sanz-Villafruela, Alba Deyà, Marta Redrado, Valentin V Novikov and 6 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Recent Advances in Two-Photon-Activatable Metal Complexes for Photodynamic Therapy.Angewandte Chemie (International ed. in English) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Diego Abad-MonteroDepartament de Química Inorgànica i Orgànica, Secció de Química Orgànica, Universitat de Barcelona (UB), Institut de Biomedicina de la Universitat de Barcelona (IBUB), Martí i Franquès 1-11, E-08028 Barcelona, Spain.ORCID 0000-0003-4138-7785
Eduardo Izquierdo-GarcíaDepartament de Química Inorgànica i Orgànica, Secció de Química Orgànica, Universitat de Barcelona (UB), Institut de Biomedicina de la Universitat de Barcelona (IBUB), Martí i Franquès 1-11, E-08028 Barcelona, Spain.ORCID 0000-0002-7253-6934
Pierre MesdomChimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, F-75005 Paris, France.
Albert GandiosoDepartament de Química Inorgànica i Orgànica, Secció de Química Orgànica, Universitat de Barcelona (UB), Institut de Biomedicina de la Universitat de Barcelona (IBUB), Martí i Franquès 1-11, E-08028 Barcelona, Spain.
Elena de la Torre-RubioDepartament de Química Inorgànica i Orgànica, Secció de Química Orgànica, Universitat de Barcelona (UB), Institut de Biomedicina de la Universitat de Barcelona (IBUB), Martí i Franquès 1-11, E-08028 Barcelona, Spain.
Manel BoschUnitat de Microscòpia Òptica Avançada, Centres Científics i Tecnològics, Universitat de Barcelona, Av. Diagonal 643, E-08028 Barcelona, Spain.ORCID 0000-0001-5870-6346
Juan Sanz-VillafruelaDepartamento de Química, Facultad de Ciencias, Universidad de Burgos, Plaza Misael Bañuelos s/n, E-09001 Burgos, Spain.
Alba DeyàHealth and Biomedicine Department, Leitat Technological Center, Carrer de la Innovació 2, E-08225 Terrassa, Spain.
Marta RedradoChimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, F-75005 Paris, France.ORCID 0000-0001-5201-0874
Valentin V NovikovDepartament de Química Inorgànica i Orgànica, Secció de Química Inorgànica, Universitat de Barcelona (UB), and Institute of Nanoscience and Nanotechnology of the University of Barcelona (IN2UB), Martí i Franquès 1-11, E-08028 Barcelona, Spain.ORCID 0000-0002-0225-0594
José Luis HernándezHealth and Biomedicine Department, Leitat Technological Center, Carrer de la Innovació 2, E-08225 Terrassa, Spain.
Jorge GalinoHealth and Biomedicine Department, Leitat Technological Center, Carrer de la Innovació 2, E-08225 Terrassa, Spain.
Marta E AlbertoDipartimento di Chimica e Tecnologie Chimiche, Università Della Calabria, Arcavacata di Rende I-87036, Italy.ORCID 0000-0001-9925-7233
Antonio Francés-MonerrisInstitut de Ciència Molecular, Universitat de València, P.O. Box 22085, València 46071, Spain.ORCID 0000-0001-8232-4989
Gilles GasserChimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, F-75005 Paris, France.ORCID 0000-0002-4244-5097
Vicente MarchánDepartament de Química Inorgànica i Orgànica, Secció de Química Orgànica, Universitat de Barcelona (UB), Institut de Biomedicina de la Universitat de Barcelona (IBUB), Martí i Franquès 1-11, E-08028 Barcelona, Spain.ORCID 0000-0002-1905-2156

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) is a promising cancer treatment modality, offering precise spatial and temporal control of drug activation using light. However, clinical translation of current photosensitizers (PSs) is limited by inefficient activation at wavelengths within the phototherapeutic window, especially in the deep-red and near-infrared (NIR) region. NIR light provides advantages such as reduced absorption by endogenous chromophores, minimized tissue photodamage, and improved tissue penetration, highlighting the need for PSs to be activatable in this range. Herein, we report a novel series of ruthenium(II) polypyridyl complexes (

Indexed as

Antineoplastic AgentsCoordination ComplexesPhotochemotherapyPhotosensitizing AgentsRutheniumAnimalsCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansInfrared RaysMiceMolecular StructurePhotonsReactive Oxygen SpeciesAntineoplastic AgentsCoordination ComplexesPhotosensitizing AgentsReactive Oxygen SpeciesRuthenium

Identifiers

PMID41355180
PMCPMC12715793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.