Evidence map›Paper›PMID 41355127›Full record

ArticleZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2025

[Advantages and challenges of auxiliary liver transplantation therapeutic strategies for patients with acute liver failure].

L Y Sun, L Wei, W Qu, Z G Zeng, H M Zhang, Z J Zhu

Abstract readEnglish Abstract
In one paragraph

Article in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

L Y SunDepartment of Critical Liver Disease, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Liver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing 100050, China.
L WeiLiver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing 100050, China.
W QuLiver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing 100050, China.
Z G ZengLiver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing 100050, China.
H M ZhangLiver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing 100050, China.
Z J ZhuLiver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing 100050, China.

Funding

Beijing Tongzhou District Science and Technology Innovation Talent Funding Program CXTD2024007Capital's Funds for Health Improvement and Research 2024-1-2022
6 · The paper itself

Abstract

The mortality rates are significantly elevated with the rapid progression of acute liver failure in the absence of timely diagnosis and treatment. Liver transplantation is an effective therapeutic approach that can halt disease progression, but transplantation timing is a crucial factor affecting prognosis. Patients with acute liver failure should be promptly transferred to hospitals equipped for liver transplantation while simultaneously preparing for the procedure during the course of treatment to avoid missing the opportunity to save lives when the condition suddenly worsens. Auxiliary liver transplantation preserves the patient's native liver while transplanting a new liver. Therefore, patients are expected to gradually reduce immunosuppressants following the regeneration of the autologous liver, so avoiding the problem of lifelong use of immunosuppressants. This is also a unique advantage, offering benefits to patients undergoing auxiliary liver transplantation therapy for acute liver failure, while simultaneously presenting challenges for clinicians in terms of technical skill and comprehensive management.

Indexed as

Liver Failure, AcuteLiver TransplantationHumansImmunosuppressive AgentsImmunosuppressive Agents

Identifiers

PMID41355127
PMCPMC12861804

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.