Evidence map›Paper›PMID 41355076›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Intertidal Warfare: Synergistic Allelopathy Mediates Spatial Competition between Two Marine Calcareous-Shelled Sessile Organisms.

Zhuo Li, Zixin Huo, Shanshan Yao, Xianmeng Liang, Yiran Zhao, Yanxin Wang, Shifeng Guo, Caihuan Ke, Pei Su, Danqing Feng

Abstract read
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In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhuo LiState Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian, 361102, China.
Zixin HuoShenzhen Key Laboratory of Smart Sensing and Intelligent Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, China.
Shanshan YaoState Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian, 361102, China.
Xianmeng LiangLaoshan laboratory, Qingdao, 266237, China.
Yiran ZhaoState Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian, 361102, China.
Yanxin WangState Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian, 361102, China.
Shifeng GuoShenzhen Key Laboratory of Smart Sensing and Intelligent Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, China.
Caihuan KeState Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian, 361102, China.
Pei SuState Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian, 361102, China.
Danqing FengState Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian, 361102, China.ORCID https://orcid.org/0000-0001-7478-4870

Funding

Fujian Provincial Natural Science Foundation of China 2024J010003Independent Research Project of State Key Laboratory of Mariculture Breeding MBL25IR21National Key Research and Development Program of China 2022YFC3103904National Natural Science Foundation of China 42376090Project High-quality Development of the Marine and Fishery Industry of Fujian Province FJHYF-L-2023-14
6 · The paper itself

Abstract

Chemical warfare among marine sessile organisms remains poorly understood. Chemical defense in calcareous-shelled organisms in particular has been largely neglected, yet this may be important in spatial dominance of crowded intertidal ecosystems. Using field survey data, spatial competition in intertidal zones between two calcareous-shelled sessile species are discovered, the barnacle Balanus albicostatus and the mussel Vignadula atrata. Using chemical analysis and bioassays, it is found that B. albicostatus releases chemical cues with inhibitory activity against the attachment of V. atrata. This allelochemical is identified as a blend of palmitic acid (PA) and 1-palmitoyl-sn-glycero-3-phosphocholine (PGPC) in a synergistic and unique ratio (1:1.92). This mixture of PA and PGPC synergistically reduced byssus thread production, adhesive plaque area and adhesion force of mussel foot proteins (MFPs) in V. atrata. Further analysis showed that this mixture down-regulated expression of the genes associated with byssus formation and adhesion (PreCol-NG, MFP2, MFP11, Tyr, BPP4, and PPO) and led to a lower activity of the enzyme polyphenol oxidase essential to mussel attachment, implying an underlying mechanism by which allelochemicals inhibit mussel attachment. This underlines the importance of allelopathy in interspecies competition between calcareous-shelled sessile organisms and provides information which may be useful for developing novel biofouling control systems.

Indexed as

AllelopathyAquatic OrganismsBivalviaPheromonesThoracicaAnimalsEcosystemPheromonesallelopathyattachmentchemical ecologymarine sessile organismssynergistic effect

Identifiers

PMID41355076
PMCPMC12931170

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.