Evidence map›Paper›PMID 41354746›Full record

SynthesisScientific reports2025

Acceptance of preventive therapy for latent tuberculosis infection in Chinese children and adolescents: a systematic review and meta-analysis.

Liai Peng, Yiqing Zhou, Min Wang, Zhipeng Zu, Qian Wu, Xinyi Chen, Yu Zhang, Bo Xie, Bin Chen, Yunxia Wang

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liai Peng *Department of Tuberculosis Control and Prevention, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, China.
Yiqing Zhou *School of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Min Wang *Quzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, China.
Zhipeng ZuDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Qian WuDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Xinyi ChenDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Yu ZhangDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Bo XieSchool of Urban Design, Wuhan University, Wuhan, Hubei, China.
Bin ChenDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China. bchen@cdc.zj.cn.
Yunxia WangDepartment of Tuberculosis Control and Prevention, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, China. 85804139@qq.com.

Funding

the Bao'an District's Medical and Health Research Project 2023JD152the Guangdong Medical Research Fund A2023156the Natural Science Foundation of Shenzhen Municipality JCYJ20240815110459001the "Pioneer" and "Leading Goose" R&D Program of Zhejiang 2025C01134the Science and Technology Program on Disease Prevention and Control of Zhejiang Province 2025JK181the Shenzhen Medical Research Fund B2303003
6 · The paper itself

Abstract

Tuberculosis preventive treatment (TPT) is essential for pediatric tuberculosis control in children and adolescents. Evidence indicates most attrition occurs prior to TPT initiation rather than from post-initiation nonadherence. This study systematically evaluated TPT acceptance for latent tuberculosis infection (LTBI) among Chinese children and adolescents and identified key influencing factors through comprehensive database searches (PubMed, Web of Science, Embase, Cochrane, CNKI, Wanfang database, CBM, VIP) up to February 21, 2025. The heterogeneity was assessed using I

Indexed as

Antitubercular AgentsLatent TuberculosisPatient Acceptance of Health CareAdolescentChildChild, PreschoolChinaEast Asian PeopleFemaleHumansAntitubercular AgentsAcceptanceAdolescentsChildrenLatent tuberculosis infectionPreventive therapy

Identifiers

PMID41354746
PMCPMC12796291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.