Evidence map›Paper›PMID 41354030›Full record

ArticleClinical and experimental reproductive medicine2025

Assisted reproductive technology trends in Korea: Annual report for 2022.

Dayong Lee, Myeong Eun Seong, Hye Jin Chang, Young Sik Choi, Hee Jin Lim, Youngjun Choi, Kyungjoo Hwang, Jin Suk Jo, Jung Ryeol Lee

Abstract read
In one paragraph

Article in Clinical and experimental reproductive medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dayong LeeDepartment of Obstetrics and Gynecology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Myeong Eun SeongTertiary General Hospital Designation Division, Health Insurance Review and Assessment Service, Wonju, Republic of Korea.
Hye Jin ChangDepartment of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Republic of Korea.
Young Sik ChoiInstitute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.
Hee Jin LimTertiary General Hospital Designation Division, Health Insurance Review and Assessment Service, Wonju, Republic of Korea.
Youngjun ChoiBureau of Population and Child Policy, Ministry of Health and Welfare, Sejong, Republic of Korea.
Kyungjoo HwangDepartment of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Republic of Korea.
Jin Suk JoSelf-monitoring Management Division, Health Insurance Review and Assessment Service, Wonju, Republic of Korea.
Jung Ryeol LeeDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe Korean government implemented national insurance coverage for infertility treatment in 2017 and established a nationwide infertility treatment data collection system in 2018. This report analyzes infertility treatment cycles performed in 2022 based on this national registry.

methodsData were retrospectively collected from 201 certified infertility treatment institutions in Korea. Standardized treatment forms for intrauterine insemination (IUI) and in vitro fertilization (IVF) were submitted to the Health Insurance Review and Assessment Service for all infertility treatment cycles conducted in 2022.

resultsA total of 200,007 infertility treatment cycles were reported in 2022, consisting of 33,137 IUI cycles and 166,870 IVF cycles. Among IVF cycles, 64.6% were initiated for fresh embryo transfers and 35.4% for frozen-thawed embryo transfers. In IVF cycles, the overall clinical pregnancy rate per embryo transfer was 30.2% for fresh and 42.0% for frozen-thawed embryo transfers. The proportion of single embryo transfers has risen steadily since 2019. The most common indication for IVF was diminished ovarian reserve, while IUI was mainly performed for unexplained or male factor infertility.

conclusionNationwide infertility treatment cycle reporting in Korea has enabled detailed monitoring of infertility treatment trends and outcomes. The data show a substantial increase in IVF utilization, a growing preference for frozen-thawed embryo transfer, and broader adoption of single embryo transfer consistent with global practices. Further integration with birth outcome data and longitudinal patient tracking will be essential to evaluate cumulative success rates and overall effectiveness. This national registry provides a foundation for optimizing infertility care and facilitates international benchmarking.

Indexed as

Clinical pregnancy rateFertilization in vitroIntrauterine inseminationKoreaReproductive techniques, assisted

Identifiers

PMID41354030
PMCPMC12682406

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.