Evidence map›Paper›PMID 41353733›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2026

Manipulation under anaesthesia and/or lysis of adhesions prior to revision total knee arthroplasty increases the risk of subsequent revision.

Kevin D Plancher, Elias Schwartz, Carlo Mannina, Karen K Briggs, Stephanie C Petterson

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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kevin D PlancherDepartment of Orthopaedic Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York, USA.ORCID https://orcid.org/0000-0001-9098-4258
Elias SchwartzPlancher Orthopaedics & Sports Medicine, New York City, New York, USA.
Carlo ManninaPlancher Orthopaedics & Sports Medicine, New York City, New York, USA.
Karen K BriggsPlancher Orthopaedics & Sports Medicine, New York City, New York, USA.
Stephanie C PettersonOrthopaedic Foundation, Stamford, Connecticut, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to determine if prior manipulation under anaesthesia (MUA) and/or lysis of adhesions (LOA) was associated with an increased risk of re-revision following index revision total knee arthroplasty (TKA) in patients that had a diagnosis of arthrofibrosis.

methodsThe PearlDiver Mariner database was queried by Current Procedural Terminology (CPT) and International Classification of Disease (ICD) codes to identify patients who had a diagnosis of arthrofibrosis at the time of revision TKA. Patients were divided into two groups: those with prior MUA and/or LOA and those without prior MUA and/or LOA. The groups were 1:3 propensity score matched by age, gender, anemia, and Elixhauser Comorbidity Index (ECI). The primary outcome was incidence of re-revision TKA at 5 years. Secondary outcomes included periprosthetic joint infection (PJI) at 6 months and 5 years, 90-day hospital readmission, and the incidence of deep vein thrombosis (DVT), blood transfusion, and acute kidney injury (AKI) at 6 months. Logistic regression was used to determine predictors of re-revision TKA.

resultsAfter propensity matching, 2622 patients with a diagnosis of arthrofibrosis underwent index revision TKA without prior MUA and/or LOA and 874 patients underwent index revision after a prior LOA and/or MUA. The incidence of re-revision TKA at 5 years in patients with prior MUA and/or LOA (20% vs. 14%; OR 1.5, 95% confidence interval [CI] [1.3-1.9], p < 0.001) was significantly higher compared to patients with no prior MUA and/or LOA. Predictors of re-revision were age, ECI, and prior MUA and/or LOA (OR: 1.5, 95% CI [1.2-1.9]) (R

conclusionA history of prior MUA and/or LOA, older age, and ECI are associated with a significantly higher risk of re-revision TKA in patients that have a diagnosis of arthrofibrosis at the time of index revision TKA. LEVEL OF EVIDENCE: Level III, retrospective comparative study.

Indexed as

Arthroplasty, Replacement, KneeReoperationAgedFemaleFibrosisHumansMaleMiddle AgedPatient ReadmissionPostoperative ComplicationsPropensity ScoreProsthesis-Related InfectionsRetrospective StudiesRisk FactorsTissue AdhesionsarthrofibrosisLOAMUAre‐revision TKArevision TKA

Identifiers

PMID41353733
PMCPMC13502417

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.