Evidence map›Paper›PMID 41353509›Full record

ArticleScientific reports2025

Investigating the binding potential of the Melissa officinalis oil against Alzheimer's targets by molecular docking and in vitro evaluations.

Atiyeh Kolouei, Mohammad Barati, Mahdi Abbas-Mohammadi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Atiyeh KoloueiDepartment of Applied Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran.
Mohammad BaratiDepartment of Applied Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran. barati.m@kashanu.ac.ir.
Mahdi Abbas-MohammadiDepartment of Phytochemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran. m.mohammadi@kashanu.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder with limited treatment options. Melissa officinalis (M. officinalis), traditionally used for its medicinal properties, contains compounds that may offer therapeutic benefits for AD. We extracted essential oils from M. officinalis using supercritical CO

Indexed as

Alzheimer DiseaseMelissaMolecular Docking SimulationOils, VolatilePlant OilsAcetylcholinesteraseAmyloid beta-PeptidesAmyloid Precursor Protein SecretasesAnimalsAntioxidantsCell SurvivalHumansPC12 CellsRatsAcetylcholinesteraseAmyloid beta-PeptidesAmyloid Precursor Protein SecretasesAntioxidantsOils, VolatilePlant OilsAlzheimerGC–MSMelissa officinalisMolecular dockingSupercritical extraction

Identifiers

PMID41353509
PMCPMC12779642

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.