Evidence map›Paper›PMID 41353401›Full record

ArticleScientific reports2025

Gender-specific function of melatonin receptor (MTRI) in gonads of red swamp crayfish, Procambarus clarkii.

Meng Hu, Long Wang, Qianqian Zhu, Tianyu Guan, Yurui Wang, Lin Cai, Hui Wang, Jiale Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meng HuJiangsu Engineering Center for Breeding of Special Aquatic Organisms, Huaiyin Normal University, Huai'an, 223300, China.
Long WangJiangsu Engineering Center for Breeding of Special Aquatic Organisms, Huaiyin Normal University, Huai'an, 223300, China.
Qianqian ZhuJiangsu Engineering Center for Breeding of Special Aquatic Organisms, Huaiyin Normal University, Huai'an, 223300, China.
Tianyu GuanTaizhou Haida Biological Feed Co., Ltd., Taizhou, 225300, China.
Yurui WangJiangsu Engineering Center for Breeding of Special Aquatic Organisms, Huaiyin Normal University, Huai'an, 223300, China.
Lin CaiJiangsu Engineering Center for Breeding of Special Aquatic Organisms, Huaiyin Normal University, Huai'an, 223300, China.
Hui WangJiangsu Engineering Center for Breeding of Special Aquatic Organisms, Huaiyin Normal University, Huai'an, 223300, China. whh524@sina.com.
Jiale LiKey Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture, Shanghai Ocean University, Shanghai, 201306, China.

Funding

Jiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection, Huaiyin Normal University HSXT30312Jiangsu Provincial Agricultural Science and Technology Independent Innovation Fund CX223082Science Technology Program of Huaiyin Normal University 31WH000
6 · The paper itself

Abstract

Melatonin receptor (MTR) plays a crucial role in mediating melatonin signaling. Therefore, it is necessary to study functions and characteristics of MTR. In this study, full length cDNA of MTRI in Procambarus clarkii was cloned. The phylogenetic tree revealed that MTRI amino acid sequence of P. clarkii had the closest relationship with Homarus americanus. The temporal and spatial distribution expression results indicated that MTRI was highly expressed in gonadal tissues and eyestalk. RNA interference (RNAi) was used to identify the content of related hormones and the relative expression of genes in gonads of P. clarkii. The results showed that melatonin had an important effect on gonad of P. clarkii. Due to the specificity of the reproductive system in female and male crayfish, the siRNA interference efficiency was different, GIH, GTH, 5-HT and MT showed the opposite trend. Levels decreased in females but increased in males. However, the sex hormones E2 and T decreased, indicating that the silencing of MTRI will hinder gonadal development. This study provides a theoretical basis for further study of the role of melatonin in crustacean gonads.

Indexed as

AstacoideaGonadsReceptors, MelatoninAmino Acid SequenceAnimalsArthropod ProteinsCloning, MolecularFemaleMaleMelatoninPhylogenyRNA InterferenceArthropod ProteinsMelatoninReceptors, MelatoninGonadMelatoninMelatonin receptorProcambarus clarkii

Identifiers

PMID41353401
PMCPMC12689651

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.