Evidence map›Paper›PMID 41353358›Full record

ArticleBMC oral health2025

Antifungal activities, surface roughness, and color change of 3D printed resins containing halloysite nanotubes.

Yousif A Al-Dulaijan, Ali Alkhathami, Shahad T Alameer, Turki Alshehri, Mohammed Alotaibi, Soban Q Khan, Sultan Akhtar, Abdulrahman A Balhaddad, Mohammed M Gad

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yousif A Al-DulaijanDepartment of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia. yaaldulaijan@iau.edu.sa.
Ali AlkhathamiCollege of Dentistry, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam, 31441, Saudi Arabia.
Shahad T AlameerCollege of Dentistry, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam, 31441, Saudi Arabia.
Turki AlshehriDepartment of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.
Mohammed AlotaibiCollege of Dentistry, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam, 31441, Saudi Arabia.
Soban Q KhanDepartment of Dental Education, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.
Sultan AkhtarDepartment of Biophysics, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.
Abdulrahman A BalhaddadDepartment of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.
Mohammed M GadDepartment of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRemovable dentures are one of the common treatment modalities used to restore missing teeth. Denture stomatitis, caused by the adhesion of Candida albicans, is considered a major complication of these prostheses. The purpose of this article is to evaluate the impact of adding Halloysite Nanotubes (HNTs) on the surface roughness (Ra, µm), color change (∆E*), and Candida albicans adhesion in 3D-printed denture base resins (PDBRs).

methodsThree concentrations (0.3%,0,6%, and 0.9%wt.) of HNTs were added to two PDBRs, ASIGA and NextDent, while the control group remained without HNTs addition. The specimens were printed in a disk shape (15 × 2 mm). After printing, specimens were thermocycled (5000 cycles). Surface roughness was measured using a non-contact profilometer. Color change (∆E*) was measured using the Commission International de l'Eclairage (CIE) system coordinates (L*, a*, b*) method. C. albicans adhesion was evaluated using a colony-forming unit (CFU/mL). The collected data were statistically analyzed using ANOVA and a post-hoc Tukey test (α = 0.05).

resultsThe addition of HNTs showed no significant difference in surface roughness between all tested groups (P ˃0.05). Adding HNTs resulted in a slight color change at 0.3% and 0.6%, while 0.9% significantly increased the color change (P < 0.001) with a noticeable difference. Adding HNTs significantly decreased the C. albicans adhesion to PDBRs compared to pure resins (P < 0.001). Regarding the concentration effect, the effect was concentration-dependent, with 0.9% showing the lowest Candida colony count for ASIGA resin (1018.9 ± 80.0) and NextDent resins (911.1 ± 89.3).

conclusionAdding HNTs to PDBRs did not change the surface roughness and significantly decreased C. albicans adhesion. The color was changed with HNTs to noticeable with 0.9%HNTs. Due to the antifungal activities of PDBRs containing HNTs, these PDBRs could be recommended as a method for preventing denture stomatitis.

Indexed as

Aluminum SilicatesAntifungal AgentsDenture BasesNanotubesPrinting, Three-DimensionalCandida albicansClayColorHumansMaterials TestingSurface PropertiesAluminum SilicatesAntifungal AgentsClay3D printingC. albicansDenture baseNanotubeSurface properties

Identifiers

PMID41353358
PMCPMC12798076

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.