Evidence map›Paper›PMID 41353270›Full record

ArticleScientific reports2025

Dynamic microdevice culture during bovine oocyte maturation decreases lipid accumulation and improve blastocyst cell numbers.

Franciele Flores Vit, Juliano Rodrigues Sangalli, Mariani Farias Fiorenza, Helena Fabiana Reis de Almeida Saraiva, Juliana Germano Ferst, Felipe Perecin, Flavio Vieira Meirelles, Lucimara Gaziola de la Torre, Juliano Coelho da Silveira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Franciele Flores VitDepartment of Veterinary Medicine, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, 13635-900, SP, Brazil.
Juliano Rodrigues SangalliDepartment of Veterinary Medicine, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, 13635-900, SP, Brazil.
Mariani Farias FiorenzaDepartment of Veterinary Medicine, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, 13635-900, SP, Brazil.
Helena Fabiana Reis de Almeida SaraivaDepartment of Veterinary Medicine, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, 13635-900, SP, Brazil.
Juliana Germano FerstDepartment of Veterinary Medicine, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, 13635-900, SP, Brazil.
Felipe PerecinDepartment of Veterinary Medicine, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, 13635-900, SP, Brazil.
Flavio Vieira MeirellesDepartment of Veterinary Medicine, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, 13635-900, SP, Brazil.
Lucimara Gaziola de la TorreSchool of Chemical Engineering, Department of Materials and Bioprocesses Engineering, State University of Campinas, Av. Albert Einstein, 500, Campinas, 13083-852, SP, Brazil.
Juliano Coelho da SilveiraDepartment of Veterinary Medicine, University of São Paulo, Av. Duque de Caxias Norte, 225, Pirassununga, 13635-900, SP, Brazil. julianodasilveira@usp.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 304815/2022-5Conselho Nacional de Desenvolvimento Científico e Tecnológico 305286/2024-2Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/13075-2Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/06645-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/01235-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/02701-5
6 · The paper itself

Abstract

Assisted reproductive technology (ART) enhances livestock fertility and genetic quality while reducing disease transmission. In vitro embryo production (IVEP) is a crucial technique that requires optimization. Microfluidics has emerged as a promising platform for IVEP by offering a controlled environment with a continuous nutrient supply. This study introduces a novel non-toxic and reusable microdevice with reversible sealing designed for the in vitro maturation (IVM) of bovine cumulus oocyte complexes (COCs). The microdevice is constructed from PMMA and PDMS

Indexed as

BlastocystIn Vitro Oocyte Maturation TechniquesLipid MetabolismOocytesAnimalsCattleCell CountCumulus CellsEmbryonic DevelopmentFemaleLab-On-A-Chip DevicesReactive Oxygen SpeciesReactive Oxygen SpeciesBlastocystsCOCsIn vitro maturationMicrofluidic

Identifiers

PMID41353270
PMCPMC12770460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.