Evidence map›Paper›PMID 41352350›Full record

ArticleCurrent biology : CB2026

Retrograde optogenetics reveals sensorimotor convergence within a corticotectal pathway of non-human primates.

Xuefei Yu, Atul Gopal, Ken-Ichi Inoue, Martin O Bohlen, Genevieve M Kuczewski, Marc A Sommer, Hendrikje Nienborg, Masahiko Takada, Okihide Hikosaka

Abstract read
In one paragraph

Article in Current biology : CB, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Xuefei YuLaboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: xuefei.yu@nih.gov.
Atul GopalLaboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: pagopal@ucdavis.edu.
Ken-Ichi InoueCenter for the Evolutionary Origins of Human Behavior, Kyoto University, Inuyama, Aichi 484-8506, Japan; Laboratory of Integrative Anatomy, Graduate School of Medical Sciences and Medical School, Nagoya City University, Nagoya, Aichi 467-8601, Japan.
Martin O BohlenDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Genevieve M KuczewskiDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Marc A SommerDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Hendrikje NienborgLaboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Masahiko TakadaCenter for the Evolutionary Origins of Human Behavior, Kyoto University, Inuyama, Aichi 484-8506, Japan.
Okihide HikosakaLaboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Funding

Neuronal networks for control of eye movementZIAEY000415 · NEI · NATIONAL EYE INSTITUTE · PI HIKOSAKA, OKIHIDE · 2009 to 2025
$35.3M
Enhancement, mapping, and validation of viral vectors for primate optogeneticsR01NS125843 · NINDS · DUKE UNIVERSITY · PI Marc A Sommer · 2022 to 2026
$3.2M
Intramural NIH HHS Z99 EY999999Intramural NIH HHS ZIA EY000415NINDS NIH HHS R01 NS125843
6 · The paper itself

Abstract

Understanding how the cerebral cortex communicates with subcortical areas to drive behavior remains a central question in system neuroscience. One key unresolved issue is whether prefrontal cortical outputs to motor-related subcortical regions carry predominantly motor commands

Indexed as

Macaca mulattaOptogeneticsSuperior ColliculiAnimalsMaleNeural PathwaysSaccadesFEFmanipulationnon-human primatesopto-taggingpathway selectiveretrograde optogeneticsSCsensorimotor transformation

Identifiers

PMID41352350
PMCPMC12981381

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.