Evidence map›Paper›PMID 41352269›Full record

ArticleJournal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Total-body versus knee-specific dual-energy X-ray absorptiometry scans for assessing bone mineral density surrounding the knee joint in collegiate athletes with and without an anterior cruciate ligament reconstruction.

Keith A Knurr, James P Lyon, Neil C Binkley, Tamara A Scerpella, Bryan C Heiderscheit

Abstract readComparative Study
In one paragraph

Article in Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keith A KnurrDepartment of Orthopedics & Rehabilitation, University of Wisconsin-Madison, Madison, WI, USA; Badger Athletic Performance Program, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: knurr@ortho.wisc.edu.
James P LyonBadger Athletic Performance Program, University of Wisconsin-Madison, Madison, WI, USA.
Neil C BinkleyDepartment of Orthopedics & Rehabilitation, University of Wisconsin-Madison, Madison, WI, USA; Badger Athletic Performance Program, University of Wisconsin-Madison, Madison, WI, USA; Department of Medicine, Division of Geriatrics, University of Wisconsin-Madison, Madison, WI, USA; University of Wisconsin Osteoporosis Clinical Research Program, Madison, WI, USA.
Tamara A ScerpellaDepartment of Orthopedics & Rehabilitation, University of Wisconsin-Madison, Madison, WI, USA; Badger Athletic Performance Program, University of Wisconsin-Madison, Madison, WI, USA.
Bryan C HeiderscheitDepartment of Orthopedics & Rehabilitation, University of Wisconsin-Madison, Madison, WI, USA; Badger Athletic Performance Program, University of Wisconsin-Madison, Madison, WI, USA; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Biology of Aging and Age-Related Diseases Training GrantT32AG000213 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Rozalyn M. Anderson, Sanjay Asthana · 1991 to 2026
$9.9M
Institutional Career Development CoreKL2TR002374 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI Bo Liu, Marin Leigh Schweizer · 2017 to 2026
$9.7M
NCATS NIH HHS KL2 TR002374NCATS NIH HHS UL1 TR002373NIA NIH HHS T32 AG000213
6 · The paper itself

Abstract

Following anterior cruciate ligament reconstruction (ACLR), athletes demonstrate reduced bone mineral density (BMD) surrounding the knee that persists for years. These changes have been identified using total-body and site-specific dual-energy X-ray absorptiometry (DXA) scans. It is unknown whether these two scan types provide comparable measures of BMD. This study assessed the agreement between total-body and knee-specific DXA scans for measuring BMD of the distal femur and proximal tibia in Division I collegiate athletes with and without an ACLR. We further assessed the influence of surgical hardware on BMD with and without the use of the manual artifact correction tool in athletes post-ACLR. Collegiate athletes (healthy: 46; post-ACLR: 20) were included. Regions of interest (ROI) were placed at the 5 % and 15 % lengths of the distal femur and the proximal tibia to assess BMD of each limb on total-body and knee-specific scans. BMD values for each limb and between-limb asymmetry were compared between scan types at each ROI using Bland-Altman analyses. Mean differences are reported as total-body minus knee-specific values. Total-body scans provided significantly lower BMD than knee-specific scans for all ROIs (-0.102 to -0.038 g/cm

Indexed as

Absorptiometry, PhotonAnterior Cruciate Ligament ReconstructionBone DensityFemurKnee JointTibiaWhole Body ImagingAdolescentAdultAnterior Cruciate Ligament InjuriesAthletesFemaleHumansMaleYoung AdultAnterior cruciate ligamentAthleteBone heathKneeScreening

Identifiers

PMID41352269
PMCPMC12951734

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.