Evidence map›Paper›PMID 41351833›Full record

ArticleJournal of animal science2025

Effects of precision feeding and functional amino acid supplementation on Salmonella-challenged growing pigs under poor housing conditions.

Pedro Righetti Arnaut, Graziela Alves da Cunha Valini, Ismael França, Manoela Trevisan Ortiz, Marllon José Karpeggiane de Oliveira, Danilo Alves Marçal, Antonio Diego Brandão Melo, Alícia Zem Fraga, Amanda Faria de Oliveira, Henrique Gastmann Brand and 4 more

Abstract read
In one paragraph

Article in Journal of animal science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Pedro Righetti ArnautSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.
Graziela Alves da Cunha ValiniSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.
Ismael FrançaSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.ORCID 0000-0002-0534-6145
Manoela Trevisan OrtizSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.
Marllon José Karpeggiane de OliveiraSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.
Danilo Alves MarçalSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.
Antonio Diego Brandão MeloSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.ORCID 0000-0001-8243-7916
Alícia Zem FragaSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.
Amanda Faria de OliveiraSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.
Henrique Gastmann BrandEvonik Brasil Ltda, São Paulo 04711-904, Brazil.
John Kyaw HtooEvonik Operations GmbH, Hanau 63457, Germany.
Candido PomarSherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, Sherbrooke, Quebec J1M 0C8, Canada.
Aline RemusSherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, Sherbrooke, Quebec J1M 0C8, Canada.
Luciano HauschildSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, São Paulo 14884-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune system activation impairs pigs' growth and increases population variability. Individual precision feeding (IPF) takes into account the variability between pigs and improves the efficiency of nutrient utilization. Additionally, functional amino acid (FAA) supplementation reduces the negative impacts of immune system activation. However, the combined effect of IPF and FAA supplementation for immune-challenged pigs remains to be evaluated. We hypothesized that the combined effect of IPF and FAA supplementation would increase nutrient efficiency and reduce the effects of immune activation on pig performance. Therefore, the objective of this study was to evaluate the use of IPF and FAA supplementation on growth performance, body composition, nutrient efficiency, and the blood parameters in growing pigs raised under different sanitary conditions (SC). A total of 120 female pigs were used across two experiments. The pigs were assigned to a good (GSC) or poor (PSC) SC barns, each with 60 pigs. The GSC barn followed strict biosecurity protocols. In the PSC barn, pigs were orally inoculated with Salmonella Typhimurium and manure from a commercial swine farm was spread on the pen floor. In each SC barn, pigs were assigned to treatments arranged in a 2 × 2 factorial design. The treatments consisted of two feeding systems (FS): group-phase feeding (GPF) and IPF, and two diets: control (CN) with 100% or supplemented (AA+) with 120% of the SID Met + Cys, Thr, and Trp to Lys ratios above Inraporc recommendations. All pigs had ad libitum access to water and feed during the 28-d experimental period. The PSC increased rectal temperature and haptoglobin concentration compared with d 0 (P < 0.05). The IPF impaired the growth performance and body composition under GSC and PSC (P < 0.05). The performance of IPF pigs increased when fed AA+ diets under GSC, but no dietary effects were observed under PSC (P > 0.05). Group-phase feeding pigs ingested more SID Lys under both SC but had the same Lys efficiency of IPF under PSC (P > 0.05). Large fluctuations in body weight and daily feed intake might have impaired the IPF model's ability to estimate SID Lys requirements. In conclusion, FAA supplementation above the InraPorc recommendations did not mitigate the adverse effects of immune challenge on growth performance or improve nutrient utilization efficiency in IPF pigs.

Indexed as

Amino AcidsHousing, AnimalSalmonella Infections, AnimalSwine DiseasesAnimal FeedAnimal HusbandryAnimal Nutritional Physiological PhenomenaAnimalsBody CompositionDietDietary SupplementsFemaleSalmonella typhimuriumSwineAmino Acidsamino acidsbody compositionimmune challengeindividual feedingnutrient efficiency

Identifiers

PMID41351833
PMCPMC12687583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.