Evidence map›Paper›PMID 41351389›Full record

ReviewRevista de neurologia2025

Oculomotor Nerve Palsy Secondary to Posterior Communicating Artery Aneurysm: A Narrative Review and Proposed Treatment Algorithm.

Yuanhong Ge, Qingjia Lai, Yunsen Zhang, Yao Wang, Xuejun Xu

Abstract readReview
In one paragraph

Review in Revista de neurologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuanhong GeDepartment of Neurosurgery, Chengdu Second People's Hospital, 610017 Chengdu, Sichuan, China.
Qingjia LaiDepartment of Rehabilitation, Care Alliance Rehabilitation Hospital of Chengdu, 610000 Chengdu, Sichuan, China.
Yunsen ZhangDepartment of Neurosurgery, Chengdu Second People's Hospital, 610017 Chengdu, Sichuan, China.
Yao WangDepartment of Neurosurgery, Chengdu Second People's Hospital, 610017 Chengdu, Sichuan, China.
Xuejun XuDepartment of Neurosurgery, Chengdu Second People's Hospital, 610017 Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOculomotor nerve palsy (ONP) is a condition characterized by ptosis, restricted eye movement, and pupillary abnormalities, with causes ranging from congenital to acquired factors. Among these, posterior communicating artery aneurysm (PcomA) represents the most clinically urgent due to the risk of rupture. Despite its significance, no standardized treatment guidelines currently exist. This narrative review aims to summarize current treatment approaches and provide a decision-making framework for clinicians.

methodsA literature review was conducted using Web of Science and PubMed from inception to December 30, 2024, with additional sources identified via manual reference searches.

resultsBoth aneurysm clipping and endovascular therapy are effective for treating PcomA-induced ONP. Endovascular techniques include coil embolization, stent- or balloon-assisted coiling, flow diverter placement, and intrasaccular flow disruption device placement. Surgical clipping is preferred in younger patients (under 60 years old), those with ONP symptoms longer than 7 days, an aneurysm size ≥7 mm, or complete ONP. In contrast, endovascular therapy is recommended for older patients, those in poor health, or undergoing treatment with antithrombotic agents. Emerging evidence suggests flow diverter placement is a promising direction, though further research is warranted.

conclusionThis review proposes a therapeutic algorithm to aid in clinical decision-making. The choice between aneurysm clipping and endovascular therapy should be individualized, taking into account patient-specific clinical factors.

Indexed as

AlgorithmsIntracranial AneurysmOculomotor Nerve DiseasesClinical Decision-MakingEmbolization, TherapeuticEndovascular ProceduresHumansclippingendovascular treatment (EVT)oculomotor nerve palsy (ONP)posterior communicating artery aneurysm (PcomA)recoveryreview

Identifiers

PMID41351389
PMCPMC12681010

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.