ArticleWorld journal of surgery2026
Safety of In-Hospital Delay of Appendectomy in Elderly Patients-A Retrospective Analysis of 525 Consecutive Patients Aged 65 and Older Undergoing Surgery for Suspected Appendicitis.
Article in World journal of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Association Between Age and Severity of Acute Appendicitis in Adults.Life (Basel, Switzerland) · 2026Article
- Impact of Disease Severity and Age on Outcomes After Laparoscopic Versus Open Appendectomy: A Single-Center Retrospective Cohort Study.Life (Basel, Switzerland) · 2026Article
- Safety of In-Hospital Delay of Appendectomy in Elderly Patients-A Retrospective Analysis of 525 Consecutive Patients Aged 65 and Older Undergoing Surgery for Suspected Appendicitis.World journal of surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent retrospective and prospective studies have demonstrated the safety of delayed surgery for acute appendicitis. However, evidence regarding delayed surgery in elderly patients is limited, and it is unclear whether it is safe to delay appendectomy in this patient population.
methodsThe outcomes of patients aged 65 years and older who underwent appendectomy for suspected appendicitis at a single institution were reviewed and analyzed. The outcomes investigated were perforation rate and complication rate. Multivariable logistic regression analysis was performed to adjust for risk factors and calculate adjusted odds ratios (aOR) for in-hospital delay.
resultsA total of 525 patients aged 65 years and older underwent appendectomy for suspected appendicitis. The perforation rate was 44.4% (233 of 525) and the complication rate was 25.1%. The multivariable analysis showed no association between a waiting time of more than 12 h compared to less than 12 h and perforation rate (aOR 0.96; 95% CI 0.55-1.70; p = 0.90) or complication rate (aOR 0.93; 95% CI 0.49-1.76; p = 0.83). A risk factor for perforation in the multivariable analysis was an elevated CRP level ≥ 50 mg/L and risk factors for complications were suspected perforation on preoperative imaging (p = 0.004), anticoagulant use (p = 0.04), and CRP levels ≥ 150 mg/L (p < 0.001).
conclusionThis large retrospective analysis showed that it is safe to delay surgery by 12 h in patients aged 65 years and older. Delayed surgery was not associated with a higher rate of perforation or complications after adjusting for risk factors. These results open the possibility of optimizing coagulation or possible comorbidities in elderly patients before surgery or postponing surgery when more critical cases require more urgent treatment. In patients with suspected perforation on imaging, the decision to delay surgery should me made with caution, taking into account the patient's overall presentation, comorbidities, and vital signs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.