Evidence map›Paper›PMID 41351206›Full record

ArticleAdvanced healthcare materials2026

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells.

Cecilia L D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin and 2 more

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Glutamine metabolism in health and disease.Signal transduction and targeted therapy · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cecilia L D'AntoniDepartamento De Química Biológica De La Facultad de Ciencias Exactas y Naturales Universidad De Buenos Aires, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-7352-1857
Leila Pourtalebi JahromiDepartment of Biology, Pharmaceutical Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Lorenzo SanaDepartment of Biology, Pharmaceutical Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Ana Paula Domínguez RubioDepartamento De Química Biológica De La Facultad de Ciencias Exactas y Naturales Universidad De Buenos Aires, Buenos Aires, Argentina.
Maja DorfnerDepartment of Biology, Pharmaceutical Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Jennifer MunkertDepartment of Biology, Pharmaceutical Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Heike DanzerDeutsches Zentrum Immuntherapie (DZI) and Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-Universiät Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
Philipp ArnoldInstitute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany.
Mikhail LebedevDepartment of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.ORCID https://orcid.org/0000-0001-7461-0977
Esther ZaninDepartment of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Oscar E PérezDepartamento De Química Biológica De La Facultad de Ciencias Exactas y Naturales Universidad De Buenos Aires, Buenos Aires, Argentina.
Gregor FuhrmannDepartment of Biology, Pharmaceutical Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.ORCID https://orcid.org/0000-0002-6688-5126

Funding

Deutsche Forschungsgemeinschaft FOR 2886/2Deutscher Akademischer Austauschdienst - DAAD 57660890
6 · The paper itself

Abstract

Probiotics are live microorganisms known for their health benefits; however, they may pose risks for immunocompromised individuals. This study explores the potential of postbiotics, specifically membrane vesicles (MVs) derived from Lacticaseibacillus casei BL23, as a safer alternative. MVs are isolated via ultracentrifugation (UC) followed by size exclusion chromatography (SEC), revealing a mean size of 178 nm and a concentration of 2.53×10

Indexed as

Escherichia coliLacticaseibacillus caseiLeukocytes, MononuclearAnimalsCaco-2 CellsCaenorhabditis elegansCytokinesHumansCytokinesantimicrobial activityimmune responsemembrane vesiclesprobiotics

Identifiers

PMID41351206
PMCPMC13107934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.